宫颈癌低剂量率后装腔内放射治疗的远期疗效

目的 评价Gynatron低剂量率后装腔内治疗机的疗效。方法 总结1980年4月－1986年6月间,应用Gynatron后装机配合^60Co治疗机进行根治性放疗的136例宫颈癌,并与镭疗及高剂量率腔内后装治疗进行比较分析。结果 除5例失访外,全部患者随访超过15年,随访率96.3%（131／136）。Ⅱ、Ⅲ期的10年生存率分别为83.9%和43.2%。总10年生存率为63.5%。放射性直肠炎发生率为12.5%（17／136）,放射性膀胱炎发生率9.6%（13／136）。结论 Gynatron低剂量率后装腔内治疗系统虽然有一定局限性,但仍可获得较满意的疗效;其治疗并发症患者可以接受,放射性直肠炎、放射性膀胱炎发生率高于镭疗,低于高剂量率腔内后装放疗。

Low-dose rate intracavitary afterloading radiotherapy for cancer of uterine cervix

OBJECTIVE: To evaluate the results of Gynatron low dose rate (LDR) brachytherapy for cancer of uterine cervix. METHODS: From April 1980 to June 1986, 136 patients with uterine cervical carcinoma were given radical radiotherapy through LDR afterloading irradiation and (60)Co external irradiation, compared with those through radium and high dose rate (HDR) intracavitary therapy. RESULTS: All patients except 5 were followed up for 15 years with a follow-up rate of 96.3% (131/136). The overall 10-year survival rate was 63.5%. The 10-year survival rates of stage II and III patients were 83.9% and 43.2%. The frequency of proctitis and cystitis were 12.5% (17/136) and 9.6% (13/136). CONCLUSION: Gynatron LDR system has achieved good results with tolerable complications including proctitis and cystitis which are more often than those of radium and less so than those of HDR.