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心脏移植中右心功能不全的预防和处理
引用本文:张东升,姬尚义,王小雷,杨建安,陈伟新.心脏移植中右心功能不全的预防和处理[J].广州医学院学报,2006,34(5):11-13.
作者姓名:张东升  姬尚义  王小雷  杨建安  陈伟新
作者单位:深圳市孙逸仙心血管医院,广东,深圳,518001
摘    要:目的:探讨心脏移植手术中造成右心功能不全的原因及其防治方法.方法:11例实施同种异体原位心脏移植手术病人监测围手术期肺动脉压力、肺循环阻力、中心静脉压和右心功能.预防性给予前列腺素E1,术后吸入NO.结果:本组病例无死亡,11例病人术中肺动脉压力有所下降,中心静脉压均有不同程度升高,1例病人出现右心功能不全表现.结论:术前正确评估肺动脉压力和右心功能,采取综合措施积极有效地降低肺动脉压,减轻右心负荷是避免或减轻右心功能不全的关键.

关 键 词:心脏移植  高血压  肺性  心室功能障碍  
文章编号:1008-1836(2006)05-0011-03
收稿时间:01 18 2006 12:00AM
修稿时间:2006年1月18日

Prevention and Treatment of Right Graft Heart Dysfunction after Heart Transplantation
ZHANG Dong-sheng,JI Shang-yi,WANG Xiao-lei,YANG Jian-an,CHEN Wei-xin.Prevention and Treatment of Right Graft Heart Dysfunction after Heart Transplantation[J].Academic Journal of Guangzhou Medical College,2006,34(5):11-13.
Authors:ZHANG Dong-sheng  JI Shang-yi  WANG Xiao-lei  YANG Jian-an  CHEN Wei-xin
Institution:Sun Yat-sen Cardiovascular Hospital, Shenzhen, Guangdong 518001, China
Abstract:Objective:To explore the cause and management of right graft heart dysfunction after transplantation.Methods:11 patients with end-stage dilated cardicomyopathy underwent orthotopic heart transplantation.Pulmonary arterial pressure(PAP),pulmonary vascular resistance(PVR),central vein pressure(CVP) and right graft heart function were monitored by Swan-Ganz catheter during the operation.Prostaglandin E1 was administered slowly via Swan-Ganz catheter before transplantation and inhaled NO postoperation.Results:Pulmonary arterial pressure of all patients decreased to a certain extent.One patient appeared right graft heart dysfunction and nobody died.Conclusion:Proper evaluation of preoperative status of PAP and right heart performance,in combination of aggressive reduction of PAP and right heart burden,may critically contribute to prevention or amelioration of graft heart.
Keywords:heart transplantation  hypertension  pulmonary  ventriculan dysfunction  right
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