Comprehensive assessment of the severity and mechanism of aortic regurgitation using multidetector CT and MR |
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Authors: | Céline Goffinet Valérie Kersten Anne-Catherine Pouleur Jean-Benoit le Polain de Waroux David Vancraeynest Agnès Pasquet Jean-Louis Vanoverschelde Bernhard L Gerber |
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Institution: | (1) Cardiology Division, Cliniques Universitaires St. Luc UCL, Av Hippocrate 10/2806, 1200 Woluwe St. Lambert, Belgium; |
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Abstract: | Recent studies have suggested that both cardiac magnetic resonance (MR) and multidetector computed tomography (MDCT) can quantify
aortic regurgitation (AR) by planimetry of the anatomical regurgitant orifice (ARO). However, this measurement was not compared
with quantitative assessment of AR such as the effective regurgitant orifice (ERO) by proximal isosurface area (PISA) transthoracic
echocardiography (TTE) or phase contrast MR. In 42 patients (34 men, age 54 ± 11 years) we compared planimetered ARO by MDCT
and MR with ERO and regurgitant volume by PISA TTE and phase contrast MR. ARO by MDCT (r = 0.87, p < 0.001) and MR (r = 0.81, p < 0.001) correlated highly with ERO by TTE. However, ARO by MDCT (27 ± 15 mm2, p < 0.001), but not by MR (23 ± 13 mm2, p = 0.58), were larger than PISA ERO (22 ± 11 mm2). ARO by MDCT (r = 0.78, p < 0.001; r = 0.85, p < 0.001) and MR (r = 0.85, p < 0.001; r = 0.87 p < 0.001) correlated well with regurgitant volume by PISA and phase contrast MR. Both MDCT (к = 0.80, p < 0.001) and MR (к = 0.84, p < 0.001) demonstrated excellent agreement in correctly assessing the mechanisms of AR, i.e. aortic root dilatation (type
I), cusp prolapse (type II) and restrictive cusp motion (type III), using surgical inspection as a reference. Measurement
of ARO by both MDCT and MR allows accurate quantitative assessment of AR. Both techniques can also accurately determine the
mechanism of AR. |
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