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门冬胰岛素30用于初发2型糖尿病患者治疗的临床疗效观察
引用本文:石小霞,贾静涛.门冬胰岛素30用于初发2型糖尿病患者治疗的临床疗效观察[J].中国医药导报,2012,9(7):38-39.
作者姓名:石小霞  贾静涛
作者单位:1. 南阳医学高等专科学校第一附属医院内分泌科,河南南阳,473065
2. 河南省南阳市第九人民医院心内科,河南南阳,473000
摘    要:目的观察门冬胰岛素30用于初发2型糖尿病患者治疗的临床疗效。方法选择初发2型糖尿病患者90例,根据患者自愿的原则,分为对照组和观察组,每组各45例。对照组采取二甲双胍+人胰岛素30 R治疗,观察组采取二甲双胍+门冬胰岛素30治疗,比较两组患者治疗4周后FBG、2 h PG和HbA1c指标,并比较两组患者平均血糖达标时间、胰岛素用量及低血糖例数。结果治疗4周后两组患者FBG、2 h PG和HbA1c指标比较,差异均有统计学意义(t=1.703、1.735、1.784,均P〈0.05);平均血糖达标时间、胰岛素用量及发生低血糖例数比较,差异均有统计学意义(t=1.713、1.774和χ2=3.873,均P〈0.05),观察组优于对照组。结论采用胰岛素治疗初发2型糖尿病患者时,首选门冬胰岛素30可提高临床疗效并降低低血糖的发生率

关 键 词:门冬胰岛素30  人胰岛素30  R  二甲双胍  初发2型糖尿病  临床疗效

The clinical effect observation of Insulin Aspart 30 for the patients with the newly diagnosed type 2 diabetes
SHI Xiaoxia , JIA Jingtao.The clinical effect observation of Insulin Aspart 30 for the patients with the newly diagnosed type 2 diabetes[J].China Medical Herald,2012,9(7):38-39.
Authors:SHI Xiaoxia  JIA Jingtao
Institution:1.Department of Endocrinology,the First Affiliated Hospital of Nanyang Medical College,He’nan Province,Nanyang 473065,China;2.Department of Cardiology,the Ninth People’s Hospital of Nanyang City,He’nan Province,Nanyang 473000,China
Abstract:Objective To observe the clinical effect of Insulin Aspart 30 for the patients with the newly diagnosed type 2 diabetes.Methods 90 patients with the newly diagnosed type 2 diabetes were divided into the control group(45 cases) and the observation group(45 cases),the FBG,2 h PG and HbA1c after 4 weeks’ treatment,the average time for blood glucose,the insulin dosage and the number of cases with low blood sugar were compared.Results After 4 weeks’ treatment,the FBG,2 h PG and HbA1c were compared,there were significant differences in the two groups(t = 1.703,1.735,1.784,all P < 0.05).The average time for blood glucose,the insulin dosage and the number of cases with low blood sugar were compared,there were significant differences in the two groups(t = 1.713,1.774 and χ2 = 3.873,all P < 0.05) in the above aspects,the observation group was better than the control group.Conclusion When the patients with newly type 2 diabetes are treated with Insulin,Insulin Aspart 30 should be used to improve the clinical effect and reduce the incidence of low blood sugar.
Keywords:Insulin Aspart 30  Human Insulin 30 R  Metformin  Newly diagnosed type 2 diabetes  Clinical effect
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