非酒精性脂肪性肝病人群调查及相关因素分析

目的观察非酒精性脂肪性肝病(NAFLD)在我区人群中的发病情况及其与体质量指数(BMI)、血糖、血脂、血压等代谢性因素的关系。方法将2010年在我院体检中心体检并诊断为NAFLD的患者216例作为A组,在其中随机抽取312例正常者作为B组。分析两组上述代谢性因素及丙氨酸氨基转移酶(ALT)之间的关系。结果 NAFLD在我区人群中的发病率为8.4%,A组在BMI、血糖、血脂、ALT等方面明显高于B组(P<0.01)。结论 NAFLD发病率较高,已成为慢性肝病最常见的原因之一。在NAFLD中存在明显的超重或肥胖及血糖、血脂的异常。

Investigation of the Patients with Non-alcoholic Fatty Liver Disease and Analysis on the Related Factors

Objective To observe the incidence of non-alcoholic fatty liver disease(NAFLD)in our areas and its relationship with BMI,blood glucose,blood lipid,and blood pressure etc..Methods 216 cases with NAFLD who have taken physical examinations in our hospital in 2010 as group A.Then 312 normal cases were randomly selected as group B.An analysis on the relationship between metabolic factors and ALT in the two groups was done.Results The incidence of NAFLD in our areas was 8.4%.The group A was obviously higher than the control group(P<0.01)in BMI,blood glucose,blood lipid etc. Conclusion The incidence of NAFLD is relatively high and it has become one of the most common reasons of chronic liver disease.Obvious overweight or abnormality in blood glucose and blood lipid exist in NAFLD.