雌激素与动脉粥样硬化

雌激素用来防治动脉粥样硬化(AS)已经成为近年来的热点。研究表明,雌激素抗AS的机制大多与其对血管内皮、血管平滑肌、血脂的调节及抗凝血等作用有关。AS的免疫-炎症理论为研究抗AS的机制提供了新的思路。雌激素替代疗法尚存在争议,植物类雌激素及中药复方类雌激素应用逐渐被人们所重视。现就雌激素与AS关系的研究进行综述。

Estrogen and Atherosclerosis

The mechanism of estrogen to prevent and treat atherosclerosis(AS)has become the hotspot in recent years.Research has shown that resistance of estrogen to AS is mostly correlated with the regulation of estrogen to vascular endothelial,vascular smooth muscle,blood fat and the anticoagulant effect.The immune-inflammation theory is a new idea about atherosclerotic mechanism.Female hormone replacement therapy is still controversial,the mimic estrogen′s effects of plant estrogen and traditional Chinese herbal compound preparation are gradually recognized.Here is to make a review on current research about the correlation between estrogen and AS.