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小儿特发性血小板减少性紫癜的发病机制及治疗进展
引用本文:陈祺棠,王缉干. 小儿特发性血小板减少性紫癜的发病机制及治疗进展[J]. 医学综述, 2012, 18(7): 1062-1065
作者姓名:陈祺棠  王缉干
作者单位:钦州市第一人民医院儿科,广西,钦州,543001
摘    要:小儿特发性血小板减少性紫癜(ITP)是儿童时期最常见的出血性疾病。大多数ITP患儿预后较好,而部分患儿则转为难治性ITP。目前还没有特殊的治疗方法,这部分患儿病情反复发作、迁移不愈,不仅加重家庭负担还严重影响患儿的生活质量。目前主要的治疗方法主要有糖皮质激素、免疫抑制剂以及脾切除等,不良反应较大。该病发病机制不是很明确,病因多种多样。

关 键 词:特发性血小板减少性紫癜  发病机制  治疗

Progress of the Pathogenesis Research and Treatment of Idiopathic Thrombocytopenic Purpura in Children
CHEN Qi-tang , WANG Ji-gan. Progress of the Pathogenesis Research and Treatment of Idiopathic Thrombocytopenic Purpura in Children[J]. Medical Recapitulate, 2012, 18(7): 1062-1065
Authors:CHEN Qi-tang    WANG Ji-gan
Affiliation:1.Department of Pediatrics,Qinzhou First People′s Hospital,Qinzhou 543001,China;2.Department of Pediatrics,the First Affiliated Hospital of Guangxi Medical University,Nanning 530027,China)
Abstract:Children with idiopathic thrombocytopenic purpura,also known as immune thrombocytopenic purpura(ITP)is the most common childhood hemorrhagic disease.Most children with ITP have good prognosis,but some evolve into refractory ITP,with no specific treatment currently,who suffer from recurrence and migration of the disease,not only increasing the family′s burden but also seriously affecting the quality of life of children.At present,the main treatment is corticosteroids,immunosuppressive agents and splenectomy etc.,which have great adverse effects.Pathogenesis of the disease is not very clear,whereas there are a variety of causes.
Keywords:Idiopathic thrombocytopenic purpura  Pathogenesis  Treatment
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