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Thrombotic microangiopathy-like disorder after living-donor liver transplantation: a single-center experience in Japan |
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| Authors: | Hori Tomohide Kaido Toshimi Oike Fumitaka Ogura Yasuhiro Ogawa Kohei Yonekawa Yukihide Hata Koichiro Kawaguchi Yoshiya Ueda Mikiko Mori Akira Segawa Hajime Yurugi Kimiko Takada Yasutsugu Egawa Hiroto Yoshizawa Atsushi Kato Takuma Saito Kanako Wang Linan Torii Mie Chen Feng Baine Ann-Marie T Gardner Lindsay B Uemoto Shinji |
| Affiliation: | Tomohide Hori,Toshimi Kaido,Fumitaka Oike,Yasuhiro Ogura,Kohei Ogawa,Yukihide Yonekawa,Koichiro Hata,Yoshiya Kawaguchi,Mikiko Ueda,Akira Mori,Yasutsugu Takada,Hiroto Egawa,Atsushi Yoshizawa,Shinji Uemoto,Departments of Hepato-pancreato-biliary,Transplant and Pediatric Surgery,Kyoto University Hospital,Kyoto 606-8507,Japan Hajime Segawa,Department of Critical Care Medicine,Japan Kimiko Yurugi,Department of Transfusion Medicine and Cell Therapy,Kyoto University Hospita... |
| Abstract: | AIM:To investigate thrombotic microangiopathy (TMA)in liver transplantion,because TMA is an infrequent but life-threatening complication in the transplantation field. METHODS:A total of 206 patients who underwent living-donor liver transplantation (LDLT) were evaluated,and the TMA-like disorder (TMALD) occurred in seven recipients. RESULTS:These TMALD recipients showed poor outcomes in comparison with other 199 recipients. Although two TMALD recipients successfully recovered,the other five recipients finall... |
| Keywords: | Thrombotic microangiopathy Liver transplan-tation von Willebrand factor A disintegrin-like domain and metalloproteinase with thrombospondin type 1 motifs Complication |
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