Klinische Ergebnisse mit der denaturierten humanen Umbilikalvene (HUV) und der ovinen Kollagenprothese (Omniflow®) als kleinkalibriger prothetischer Gefäßersatz

Prosthetic bypass grafts are frequently used in lower limb bypass surgery and dialysis access surgery in the absence of suitable autologous veins. As alternatives to the available synthetic PTFE or Dacron prostheses, biological vascular prostheses, such as denaturated human umbilical veins (HUV) and ovine collagen prostheses (Omniflow®) have been used during the past two decades. Although biological prostheses exhibit a tendency for early graft thrombosis and aneurysmal degeneration they have proved to be durable vascular conduits. Historical and contemporary results with these biological materials regarding graft patency, limb salvage and biodegeneration are presented.