| 比索洛尔、依那普利和螺内酯联合治疗风湿性心脏病慢性心力衰竭的效果 |
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| 引用本文： | 管一平,邹翰琴. 比索洛尔、依那普利和螺内酯联合治疗风湿性心脏病慢性心力衰竭的效果[J]. 心脏杂志, 2011, 23(5): 623-625 |
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| 作者姓名： | 管一平 邹翰琴 |
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| 作者单位： | 宜宾市第二人民医院:1.心内科，2.超声诊断科，四川 宜宾 644000 |
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| 摘 要： | 目的:观察比索洛尔、依那普利和螺内酯联合治疗风湿性心脏病（风心病）慢性心力衰竭（心衰,CHF）对心脏重构的影响。方法: 风心病并发心衰患者86例,随机分为比索洛尔、依那普利和螺内酯联合治疗组（试药组）以及常规治疗方案对照组（对照组）。在治疗后1年测定心功能与左室内径等指标。结果: 试药组左室舒张末期内径（LVEDD）、左室收缩末期内径（LVESD）显著下降，左室射血分数（LVEF）增加显著，与对照组比较有显著差异（均P<0．05）。结论: 比索洛尔、依那普利和螺内酯联合治疗治疗风心病心力衰竭较常规治疗方法在改善心衰，阻止心脏重构方面效果更好。
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| 关 键 词： | 心脏病，风湿性 心力衰竭，慢性 依那普利 比索洛尔 螺内酯 心脏重构 |
| 收稿时间： | 2010-09-30 |
Effect of enalapril,bisoprolol and spironolactone on chronic heart failure caused by rheumatic heart disease |
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| GUAN Yi-ping,ZOU Han-qin. Effect of enalapril,bisoprolol and spironolactone on chronic heart failure caused by rheumatic heart disease[J]. Chinese Heart Journal, 2011, 23(5): 623-625 |
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| Authors: | GUAN Yi-ping ZOU Han-qin |
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| Affiliation: | GUAN Yi-ping1,ZOU Han-qin2(1.Department of Cardiology,2.Ultrasound Department,Yibin Second People's Hospital,Yibin 644000,Sichuan,China) |
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| Abstract: | AIM: To study the effect of enalapril,bisoprolol and spironolactone on chronic heart failure(CHF) caused by rheumatic heart disease(RHD).METHODS: Eighty six RHD patients with CHF were randomly divided into control group(n=43) and experimental group(n=43).The experimental group was treated with enalapril,bisoprolol and spironolactone,whereas the control group was treated with a conventional regimen.RESULTS: Left ventricular end-diastolic diameter(LVEDD) and left ventricular end-systolic diameter(LVESD) in th... |
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| Keywords: | rheumatic heart disease heart failure enalapril bisoprolol spironolactone ventricular remodeling |
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