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5小时口服葡萄糖耐量试验在诊断餐后低血糖中的应用
引用本文:黄菊芳,蒋培培,王鹂,彭妙官,许燕莉,黎福梅,廖志红.5小时口服葡萄糖耐量试验在诊断餐后低血糖中的应用[J].中华糖尿病杂志,2011(11):844-846.
作者姓名:黄菊芳  蒋培培  王鹂  彭妙官  许燕莉  黎福梅  廖志红
作者单位:中山大学附属第一医院东山院区内科,广州510080
摘    要:目的在有或无疑似餐后低血糖症状的受试者中进行5小时口服葡萄糖耐量试验(5hOGTT),探讨OGTT特征及其临床应用价值。方法共纳入27例有疑似餐后低血糖症状的受试者和41例无餐后低血糖症状的受试者,均行82.5g葡萄糖的5hOGTT。结果在无餐后低血糖症状的受试者中共筛查出低血糖6例。在有疑似餐后低血糖的受试者中共筛查出低血糖17例,低血糖再现率83%。诊断服糖后低血糖的人群中IGT伴发率达30%。结论与无餐后低血糖症状人群相比,有疑似餐后低血糖人群中服糖后低血糖的发生率高达63%,服糖后低血糖病例的IGT伴发率达29%。对有疑似餐后低血糖病例进行4hOGTT低血糖筛查敏感性达100%。

关 键 词:口服葡萄糖耐量试验  餐后低血糖

The application of 5 hours oral glucose tolerance test in diagnosising postprandial hypoglycemia
Institution:HUANG J u- fang , J IANG Pei-pei ,WANG Li ,et al. Department of Internal Medicine ,Dongshan Division ,First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China
Abstract:Objective To discuss the characteristics and clinical value of OGTT, 5-h OGTT was carried out in subjects with or without suspected postprandial hypoglycemia symptoms. Methods 27 subjects with suspected postprandial hypoglycemia symptoms and 41 subjects without postprandial hypoglycemia symptoms accepted 82.5g 5-h OGTT. Results In group without postprandial hypoglycemia symptoms, 6 cases hypoglycemia were detected. In group with suspected postprandial hypoglycemia symptoms, 17 cases hypoglycemia were detected. The reappearance rate of hypoglycemia was 83%. In all hypoglycemia cases, the incidence of IGT reached 30%. Conclusion As compared to the group without postprandial hypoglycemia symptoms, the incidence of hypoglycemia in the group with suspected post-prandial hypoglycemia symptoms is higher, reaching 63%. At the same time, the incidence of IGT reaches 29% . In patients with suspected postprandial hypoglycemia symptoms, the sensitivity of detecting hypoglycemia reaches 100% by 4-h OGTT.
Keywords:OGTT  Hypoglycemia
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