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抑郁症患者脑单光子发射计算机断层扫描显像的初步研究
引用本文:王晓明,龙存国,付红梅,郑霞清,游金辉,谢建平. 抑郁症患者脑单光子发射计算机断层扫描显像的初步研究[J]. 中国组织工程研究与临床康复, 2001, 5(3): 27
作者姓名:王晓明  龙存国  付红梅  郑霞清  游金辉  谢建平
作者单位:1. 川北医学院附属医院,南充 637007
2. 川北医学院附属医院,四川南充637007
3. 川北医学院附属医院,四川南充 637007
基金项目:四川省教委重点科研基金资助项目(99川教计164号)
摘    要:目的探讨抑郁症患者的脑血流变化。方法观察10例未经抗抑郁治疗患者脑单光子发射计算机断层扫描(SPECT)显像;并对部分患者行重复经颅磁刺激(rTMS)治疗,同时观察其脑SPECT显像变化。结果抑郁症患者左额叶血流量明显减低(5/10),且与其病情有关;rTMS能改善抑郁症额叶低灌注状态。结论抑郁症患者存在左额叶的局部血流低灌注。rTMS治疗抑郁症可能与左额叶血流低灌注改善有关。

关 键 词:抑郁症  经颅磁刺激  脑体层摄影术  发射型计算机;单光子
文章编号:1007-5496(2001)02-0027-02
修稿时间:2000-11-27

Preliminary study on brain SPECT imaging in patients with depression
WANG Xiao ming,LONG Chun guo,FU Hong mei,et al.. Preliminary study on brain SPECT imaging in patients with depression[J]. Journal of Clinical Rehabilitative Tissue Engineering Research, 2001, 5(3): 27
Authors:WANG Xiao ming  LONG Chun guo  FU Hong mei  et al.
Affiliation:WANG Xiao ming,LONG Chun guo,FU Hong mei,et al. Affiliated Hospital of North Sichuan Medical College,Nancong 637007,China
Abstract:Objective To observe the changes of regional cerebral blood flow (rCBF) in depressed patients.Methods 99mTCECD SPECT was performed on 10 depressed patients unmediated by anti- depressants. Also,To observed the changes of rCBF in 5 depressed patients treated with repetitive transcranial magnetic stiamulation( rTMS ).Results The rCBF of left frontal were decreased in depressed patients.By rTmS, the rCBF of left frontal was increased significantly.Conclusions Hypoperfusions of left frontal were identified in patients with depression rTMS could increase the rCBF in left frontal.
Keywords:depression  transcranial magnetic  stimuation  tomography  emission computed  single photon
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