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Cucurbitane-type triterpenoids from Momordica charantia
Authors:Chang Chi-I  Chen Chiy-Rong  Liao Yun-Wen  Cheng Hsueh-Ling  Chen Yo-Chia  Chou Chang-Hung
Affiliation:Graduate Institute of Biotechnology, National Pingtung University of Science and Technology, Pingtung 912, Taiwan, Republic of China.
Abstract:Five new cucurbitane-type triterpenes, (23E)-25-methoxycucurbit-23-ene-3beta,7beta-diol (1), (23E)-cucurbita-5,23,25-triene-3beta,7beta-diol (2), (23E)-25-hydroxycucurbita-5,23-diene-3,7-dione (3), (23E)-cucurbita-5,23,25-triene-3,7-dione (4), and (23E)-5beta,19-epoxycucurbita-6,23-diene-3beta,25-diol (5), together with one known triterpene, (23E)-5beta,19-epoxy-25-methoxycucurbita-6,23-dien-3beta-ol (6), have been isolated from the methanol extract of the stems of Momordica charantia. The structures of the new compounds were elucidated by spectroscopic methods.
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