| 复方甘草酸苷对SARS患者激素撤药综合征的影响 |
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| 引用本文： | 林晓兰,崔琪,王育琴,刘克敬,郭景仙,朱溢勇. 复方甘草酸苷对SARS患者激素撤药综合征的影响[J]. 中国药房, 2004, 15(6): 357-359 |
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| 作者姓名： | 林晓兰 崔琪 王育琴 刘克敬 郭景仙 朱溢勇 |
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| 作者单位： | 首都医科大学宣武医院药剂科,北京市,100053 |
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| 摘 要： | 目的 :探讨复方甘草酸苷 (GL)在SARS患者减激素治疗过程中的作用。方法 :采用回顾性分析方法 ,观察GL对SARS患者的激素撤药综合征 (HWS)相关症状和指标的影响。结果 :应用GL后可使HWS症状发生率降低 ,其中SARS患者的主要症状气短、胸闷的发生率分别由24 5 %和22 6 %降低至3 6 %(P≤0 01)和7 1 %(P≤0 05) ;乏力、肌肉关节痛、头痛的发生率分别由13 2 %、15 1 %、10 4 %降至7 2 %、14 3 %、0 %;SARS患者ALT升高例数减少 (P≤0 01)。结论 :激素撤药过程中应用GL ,可以降低HWS的发生率。
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| 关 键 词： | 复方甘草酸苷 激素撤药综合征 SARS |
| 文章编号： | 1001-0408(2004)06-0357-03 |
| 修稿时间： | 2003-07-28 |
Influence of Compound Glycyrrhizin Injection on Hormone Withdrawal Syndrome in SARS Patients |
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| LIN Xiaolan,CUI Qi,WANG Yuqin,LIU Kejing,GUO Jingxian,ZHU Yiyong. Influence of Compound Glycyrrhizin Injection on Hormone Withdrawal Syndrome in SARS Patients[J]. China Pharmacy, 2004, 15(6): 357-359 |
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| Authors: | LIN Xiaolan CUI Qi WANG Yuqin LIU Kejing GUO Jingxian ZHU Yiyong |
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| Abstract: | OBJECTIVE:To summarize the effects of compound glycyrrhizin injection(GL)on hormone withdrawal syndrome(HWS)in SARS patients.METHODS:Using contrast design,the HWS of 134 cases of SARS who had received hormone theropy was retrospectively analysed.RESULTS:Administration of GL could descend the incidence rate of symptoms of HWS,of which the incidence rates of short breath and chest distress,the main symptoms of SARS patients,dropped from 24.5%and 22.6%to 3.6%(P≤0.01)and 7.1%(P≤0.05)and the incidence of asthenia,musculoarthragia and headache decreased from 13.2%,15.1%and 10.4%to 7.2%,14.3%and 0%respectively.The number of patients with elevated ALT reduced(P≤0.01).CONCLUSION:GL can decrease the incidence of HWS. |
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| Keywords: | SARS |
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