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136例散发性戊型肝炎临床特征分析
引用本文:沈显元,阮冰,陈振娟,刘社兰. 136例散发性戊型肝炎临床特征分析[J]. 全科医学临床与教育, 2008, 6(2): 98-101
作者姓名:沈显元  阮冰  陈振娟  刘社兰
作者单位:三门县人民医院感染科;浙江大学医学院附属第一医院感染科,浙江杭州,310003
摘    要:目的探讨散发性戊型肝炎的临床特点。方法回顾性分析136例散发性戊型肝炎临床资料。结果临床表现主要有乏力130例(95.59%)、黄染119例(87.50%)、纳差104例(76.47%)。血清白蛋白(ALB)、总胆红素(TBIL)、胆碱脂酶(CHE)、凝血酶原活动度(PTA)在老年组(≥60岁)与非老年组(〈60岁)之间比较,差异均有统计学意义(t分别=5.85、3.95、3.49、4.65,P均〈0.05),在戊型肝炎重叠HBV感染组与单纯戊型肝炎组之间比较,差异亦均有统计学意义(t分别:6.75、3.68、3.83、4.53,P均〈0.05)。结论大多散发性戊型肝炎有急性肝炎典型的临床表现,且预后良好,但老年患者、重叠HBV感染者黄疸深、肝功能损害重。

关 键 词:戊型肝炎  临床特征  老年人  重叠感染
修稿时间:2008-01-24

Clinical analysis of sporadic hepatitis E in 136 cases
Affiliation:SHEN Xianyuan, RUAN Bing, CHEN Zhenjuan,et al. (Department of Infections Diseases, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China)
Abstract:Objective To explore the clinical characteristics of sporadic hepatitis E. Methods The clinical data of 136 eases with sporadic hepatitis E were analyzed retrospectively. Results The common symptoms included fatigue (95.59%), jaundice (87.50%) and anorexia (76.47%). There were significant differences of albumin (ALB), total bilirubin (TBIL), cholinesterase (CHE) and prothrombin activity (PTA) between over 60-year-old patients and younger patients (t=5.85, 3.95, 3.49, 4.65,P〈0.05), and between hepatitis E patients superinfected with HBV and hepatitis E patients (t=6.75, 3.68, 3.83, 4.53,P〈0.05). Conclusions Most of patients with sporadic hepatitis E had typical symptoms of acute hepatitis with good prognosis. The elderly patients or patients superinfected with HBV had a heavy jaundice and poor liver function.
Keywords:hepatitis E  clinical characteristics  elder  superinfection
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