| 人免疫缺陷病毒感染与血栓形成性疾病 |
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| 引用本文： | 杨咏梅,艾清龙. 人免疫缺陷病毒感染与血栓形成性疾病[J]. 国际脑血管病杂志, 2008, 16(6) |
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| 作者姓名： | 杨咏梅 艾清龙 |
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| 作者单位： | 1. 大理州人民医院神经内科,671000
2. 昆明医学院第一附属医院神经内科,650032 |
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| 摘 要： | 人免疫缺陷病毒(HIV)感染者血液中可出现抗磷脂抗体、狼疮抗凝物,von Willebrand因子、D-二聚体水平升高,蛋白S、蛋白C、抗血栓素和肝素辅因子减少,从而导致血液高凝状态.此外,HIV感染本身及继发性机会性感染也可使血管内皮受损.血液高凝状态和血管内皮损伤均可促使血栓形成性疾病的发生.
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| 关 键 词： | 人免疫缺陷病毒 获得性免疫缺陷综合征 血栓形成 |
Human Immunodeficiency Virus Infection and Thrombotic Diseases |
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| Yong-Mei Yang,Qing-Long Ai. Human Immunodeficiency Virus Infection and Thrombotic Diseases[J]. International Journal of Cerebrovascular Diseases, 2008, 16(6) |
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| Authors: | Yong-Mei Yang Qing-Long Ai |
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| Abstract: | Anti-phospholipid antibody and lupus anticoagulant appear in the blood of patients with human immunodeficiency virus (HIV)infection,which result in the increased levels of von Willebrand factor and D-dimer,and decreased the levels of protein S,protein C,antithrombin and heparin cofactor,and thus rgsult in hypercoagulation status.In addition,the HIV infection itself and secondary opportunistic infections may also cause endothelial injury.Both hypercoag ulation status and endothelial injury may promote the occurrence of thrombotic diseases. |
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| Keywords: | human immunodeficiency virus acquired immunodeficiency syndrome thrombosis |
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