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小鼠腹水型肝癌高、低转移细胞系的超微结构定量分析
引用本文:杨光,许广沅,凌茂英,吴玉玲,刘希凤,郝立宏. 小鼠腹水型肝癌高、低转移细胞系的超微结构定量分析[J]. 大连医科大学学报, 1994, 0(4)
作者姓名:杨光  许广沅  凌茂英  吴玉玲  刘希凤  郝立宏
作者单位:Dept. of Hisfoembryology,Dalian Medical Unfversity
摘    要:本文对小鼠腹水型肝癌淋巴道高转移细胞系(Hca-F25/L-16A3)和低转移细胞系(Hca-F25/L-A2)的超微结构进行了比较观察,并应用体视学方法进行了定量分析。结果表明Hca-F25/L-16A3细胞剖面平均直径、核质比较均Hca-F25/L-A2大。Hca-F25/L-16A3细胞的分裂相、核畸形、核仁边集较多见,胞质中粗面内质网、游离核糖体较丰富,细胞表面微绒毛较多。表明不同转移能力的Hca瘤细胞在形态上也有差异。

关 键 词:肝癌,Hca-F_(25)/L-16A_3,Hca-F_(25)/L-A_2,超微结构;体视学

The stereolocgical study on the ultrastructure of two morse ascites hepatoma clones with different metastatic ability
Yang Guang,et al.. The stereolocgical study on the ultrastructure of two morse ascites hepatoma clones with different metastatic ability[J]. Journal of Dalian Medical University, 1994, 0(4)
Authors:Yang Guang  et al.
Abstract:By means of stereological methods, the ultrastructure of two morse ascites hepatoma cell clones with different metastatic ability, Hca-F_(25)/L-16A_3(16A_3) and Hca-F_(25)/L-A_2 (A_2) have been analysed. The mean of diameter of cyto-sections in 16A_3 is larger than A_2 and the ratio ofnucleus to cytoplasm is great in 16A_3. Cell division, deformity of nucleus and nucleolus closing to the nuclear membrane are common in 16A_3. RER and dissociate ribosome in cytoplasm and microvilli of 16A_3cells are more than A_2. The morphology. different in the two cell clones with different metastatic ability can be seen.
Keywords:hepatoma  Hca-F_(25)/L-16A_3  Hca-F_(25)/L-A_2  ultrastructure  stereology.
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