松针提取液对高脂膳家兔血脂与脂质过氧化的影响

目的:探讨松针提取液对高脂膳家兔血脂及脂质过氧化的影响。方法:经8周高脂乳剂饲养后,选高脂血症造模成功的家兔15只,随机分为对照组、松针提取液低剂量组(治疗Ⅰ组)、松针提取液高剂量组(治疗Ⅱ组)。取血测定总胆固醇(TC)、甘油三酯(TG)、丙二醛(MDA)、超氧化物歧化酶(SOD)活性和总抗氧化活力等指标。结果:经松针提取液治疗后,血清TC、TG及MDA含量降低,SOD活性及总抗氧化活力升高,与对照组比较,治疗Ⅱ组的降脂作用和抗氧化能力更显著。结论:松针提取液对高脂膳家兔有降血脂和抗脂质过氧化的作用。

Effect of pine-needle extract on blood lipids level and lipid peroxidation in high fat diets rabbits

Objective:To study the comprehensive effect of pine-needle extract on blood lipids level and lipid peroxidation in high fat diets rabbits.Methods:15 rabbits with hyperlipidemia successfully induced by feeding hyperlipidic emulsion for 8 weeks were randomly divided into the control group,treating group I(treated with a small dose of the liquid pine needle extract)and treating group II(treated with a large dose of the extract).A certain volume of blood was drawn from the rabbits to determine the levels of TG,TC,MDA,and SOD activity,and total anti-oxidizing capacity in the serum.Results:After the treatment with the liquid pine needle extract,the levels of TC,TG and MDA were lower,and SOD activity and total anti-oxidizing capacity were higher in both treating groups;and compared with the control group,the extract showed stronger effects in treating group II.Conclusion:The extract has fairly strong effects of reducing blood lipid and resisting oxidization.