垂体转移瘤的临床与MRI表现（附16例报告）

目的：探讨垂体转移瘤的临床与MRI表现特点。方法：回顾性分析并评价16例垂体转移瘤的临床表现、MRI特点、治疗方法。结果：原发肿瘤包括乳癌7例,肺癌9例。转移灶位于垂体柄和（或）垂体后叶,呈浸润性生长,T1WI呈等、略低或等低不均匀信号,T2WI呈等、略高或等高混杂信号。其中,无明显临床表现3例,有尿崩症9例、垂体前叶功能减退4例、头痛4例、视力下降3例。9例误诊为垂体腺瘤,接受手术治疗;7例考虑垂体转移瘤,采用放射治疗为主的保守治疗,接受手术治疗与保守治疗者的疗效无明显差别（t=0.883,P〉0.05）。结论：垂体转移瘤的临床、MRI表现有一定特点,治疗方案选择需慎重。

Clinical and the MRI features of the pituitary metastasis: report of 16 cases

Objective：To investigate the clinic features and treatment of the pituitary metastasis. Methods：Sixteen patients with pituitary metastasis proved by pathology and/or typical clinical features were collected. Their clinic records, MR images and therapy were re- viewed retrospectively. Results：Primary malignant tumors including breast carcinoma （7 cases）, lung carcinoma （9 cases）. The lesions are in the pituitary stalk and/or posterior lobe, present as equal or slightly low signal on T1WI, equal or slightly high signal on T2WI, the lesion signal is inhomogeneous and/or the adjacent tissue is infiltrated in some eases. Metastases of tumors to the pituitary gland are often asymptomatie （3 eases） or present with diabetes insipidus （9 eases）, hypofunction of the anterior lobe of the pituitary gland （4 eases）, headache （4 eases）, and so on. Radiotherapy was mainly used in 7 eases diagnosed pituitary metastasis, resection surgery was used in 9 eases misdiagnosed as pituitary adenoma. The difference between these two methods of treatment was insignificant （ t = 0. 883, P 〉 0.05）. Conclusion： The pituitary metastasis usually shows some characteristic clinic and MRI signs, its therapeutic method selecting should be more careful.