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Central anticholinergic syndrome in a child: A case report
Authors:Martin Richmond,Donna Seger MD, FACEP, &#x  
Affiliation:

a Senior Resident, Department of Emergency Medicine, University Hospital, Jacksonville, Florida, USA

b Residency Education Director, Department of Emergency Medicine, Assistant Professor, Division of Emergency Medicine, Department of Surgery, University of Florida, Jacksonville, USA

Abstract:A 2-year-old boy developed classical signs and symptoms of the central anticholinergic syndrome after ingesting twenty 4-mg tablets of the antihistamine cyproheptadine (Periactin). His symptoms were dramatically reversed by the intravenous administration of physostigmine. The physiology of the anticholinergic system and physostigmine are discussed along with the indications, toxicity, and dosing of physostigmine.
Keywords:Author Keywords: central anticholinergic   physostigmine   antihistamine overdose
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