血清淀粉酶及血清IgA检测在儿童腹型过敏性紫癜诊断中的价值

目的探讨血清淀粉酶及血清IgA和总IgE在腹型过敏性紫癜（又称腹型紫癜）中的诊断价值。方法检测52例腹型过敏性紫癜患儿和69例无腹型过敏性紫癜患儿入院时的血清淀粉酶、血清IgA和总IgE水平,并与47例急性腹痛（胃、肠炎）组患儿进行比较。结果腹型组血清淀粉酶含量平均值为180.3±15.8IU,明显高于非腹型组和急性腹痛组（F=32.214,P=0.009）;腹型组血清IgA增高病例占44.2%,与非腹型组无明显差异,但两组均高于急性腹痛组（χ^2=13.73,P=0.001）;腹型组总IgE增高病例占40.4%,三组差异无统计意义（χ^2=1.80,P=0.41）。结论血清淀粉酶增高结合血清IgA增高可作为以腹痛起病的儿童过敏性紫癜诊断的参考指标,而血清总IgE意义不大。

Clinical Significance of Serum Amylase and Serum IgA in Children Henoch Purpura Patients

Objective To investigate the clinical significance of the level of serum amylase and serum IgA and total IgE in henoch-schonlein purpura patients with gastrointestinal involvement（also known as ＂Henoch purpura ＂）.Methods Levels of serum amylase and serum IgA and total IgE in henoch-schonlein purpura patients with or without abdominal pain or patients with acute abdominal pain were compared.Results The average level（180.3 ± 15.8 IU）of serum amylase of Henoch purpura patients was significantly higher than HSP patients without abdominal pain and acute abdominal pain patients （F=32.214, P=0.O09）; Ratio of cases of increased level of serum IgA in henoch purpura abdomen patients was 44.2%, and there was no significant difference with HSP patients without abdominal pain. But ratio of two groups was respectively higher than the acute abdominal pain patients group （χ^2=13.73, P=0.001）; Ratio of cases of increased level of serum IgE in Henoch purpura abdomen patients accounted for 40.4%, but there was no significant difference among the three group （χ^2=l.80, P=0.41）. Conclusion Levels of serum amylase increase and serum IgA increase conduce to diagnose HSP patients with the onset of abdominal pain, and serum total IgE has little significance.