| 炎症因子与多囊卵巢综合征相关性研究进展 |
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| 引用本文： | 刘晓梅,杜伯涛,苗瑞超. 炎症因子与多囊卵巢综合征相关性研究进展[J]. 国际免疫学杂志, 2012, 35(4): 282-285 |
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| 作者姓名： | 刘晓梅 杜伯涛 苗瑞超 |
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| 作者单位： | 哈尔滨医科大学第二临床医学院生殖中心,150086 |
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| 摘 要： | 多囊卵巢综合征(PCOS)是一种临床高度异质、病因复杂的疾病.近年研究发现,PCOS存在慢性炎症的病理生理过程,而且慢性炎症在PCOS远期并发症的发生发展中起重要作用.主要的慢性炎症因子,如C反应蛋白(CRP)、肿瘤坏死因子α(TNF-α)、白细胞介素类(IL)、单核细胞趋化蛋白-1( MCP-1)等在PCOS患者中有不同程度的升高,并且与PCOS患者胰岛素抵抗密切相关.
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| 关 键 词： | 多囊卵巢综合征 炎症因子 胰岛素抵抗 |
Correlation of Inflammatory Factors with Polycystic Ovary Syndrome |
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| LIU Xiao-mei , DU Bo-tao , MIAO Rui-chao. Correlation of Inflammatory Factors with Polycystic Ovary Syndrome[J]. International Journal of Immunology, 2012, 35(4): 282-285 |
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| Authors: | LIU Xiao-mei DU Bo-tao MIAO Rui-chao |
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| Affiliation: | . The Reproductive Center, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China |
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| Abstract: | Polycystic ovary syndrome （PCOS） is a heterogeneous and complicated disease. Recently, it has been demonstrated that chronic inflammation participates in the pathphysiological progress of PCOS. Chromic inflammution is closely related with the initiation and progression of long-term complications of PCOS. The elevated levels of main chronic inflammatory cytokines, including C-reactive protein （CRP）, Eumor Necrosis Factor-alpha （TNF-α）, Interleukins （IL） and Monocyte Chemoattractant Protein-1 （MCP-1）, are associated with insulin resistance in women with PCOS. |
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| Keywords: | Polycystic ovarian syndrome Inflammatory factors Insulin resistance |
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