123例早期梅毒临床分析

目的观察早期梅毒的临床特点及疗效,为提高早期诊治水平提供科学依据。方法对123例早期梅毒患者的临床资料进行综合分析。结果本组病例中男性76例,女性47例。Ⅰ期梅毒53例,以外生殖器硬下疳为主;Ⅱ期梅毒67例,以掌跖暗红斑、扁平湿疣及玫瑰疹为主;潜伏梅毒3例,无皮疹。123例患者USR、Trust、TI'PA试验均为阳性(100%):使用苄星青霉素治疗梅毒血清试验阴转率达95.9%。结论早期梅毒临床表现多样性,易误诊。苄星青霉素是治疗早期梅毒的首选药物。

Clinical analysis of 123 cases with early syphilis

Objective To study the clinical features and treatment of the patients with early syphilis.Method The clinical files of 123 patients with early syphilis were reviewed.Results All patients with early syphilis occurred in 76 males and 47 females.The 53 cases of primary syphilis characterized by extragenital chancres.The 67cases of secondary syphilis characterized by palmoplantar syphilis,condylomata lata and polymorphic rash.The rest 3 cases were latent syphilis without any skin lesion.The serum USR,Trust and TPPA,of these cases were all positive.After the therapy of penicillin,the serum Trust were negative in 118 cases(95.9%).Conclusion The complex and various skin damage of early syphilis may increase in missing diagnose rate.At present,Benzathini Benzylpenicillinum is still the first choice medicine for the treatment of early syphilis.