血栓通联用甲钴胺治疗2型糖尿病周围神经病变的临床观察

目的观察联合应用血栓通和甲钴胺治疗2型糖尿病周围神经病变的临床疗效。方法将96例2型糖尿病周围神经病变患者随机分为观察组（48例）和对照组（48例）。血糖达标后对照组给予甲钴胺静滴；观察组给予血栓通联合甲钴胺静滴，疗程均为4周。两组治疗前后的神经传导速度、临床症状改善情况比较。结果观察组的总有效率显著高于对照组（87．5％vs68．8％，P〈0．05）；治疗后两组的神经传导速度均有显著改善，观察组的改善效果优于对照组（P〈0．05）；治疗过程中不良反应较少。结论血栓通联合甲钴胺治疗糖尿病周围神经病变疗效显著，不良反应少，有临床推广意义。

The clinical observation of Xueshuantong combined Mecobalamin treatme ntof type 2 diabetes peripheral neuropathy

Objective To observe the clinical curative effect of the combined application of Xueshuantong and Mecobalamin in treating type 2 diabetic peripheral neuropathy. Methods 96 cases of type 2 diabetic patients with peripheral neuropathy were di- vided into the observation group （48 cases） and control group （48 cases） randomly.When blood sugar reached control goal,the con- trol group Was given Methycobal intravenous drip;the observation group was given intravenous Xueshuantong combined with mecobalamin for 4 weeks. The clinical curative effect and nerve conduction velocity of the two groups were compared.Results The total effective rate of observation group was significantly higher than that of control group（87.5% vs68.8%,P〈0.05）; nerve con- duction velocity was impmved significantly in all two groups after treatment,especially in the observation group（P〈0.05）;There was less adverse reactions during treatment.Conclusion Mecobalamin combined Xueshuantong in treatment of diabetic peripheral nea- ropathy is exact,less adverse reaction, there is clinical significance.