扩散张量纤维束成像对星形细胞瘤脑浸润的评估价值

目的探讨扩散张量纤维束成像技术评估星形细胞瘤脑浸润程度的应用前景。方法35例经病理证实的脑星形细胞瘤患者进行扩散张量纤维束成像（DTT）检查，其中低级星形细胞瘤13例，高级星形细胞瘤22例。分析肿瘤与瘤周纤维束的关系，立体观察纤维束的移位、连续性及破坏情况。结果全部病例均可清楚显示地观察白质纤维束形态，星形细胞瘤与瘤周纤维束的关系分为三种：推移、浸润、破坏。低级星形细胞瘤对邻近纤维束以推移为主（11／13），高级星形细胞瘤则以浸润（11／22）与破坏为主（9／22）。结论扩散张量纤维束成像技术可在活体内立体直观地显示纤维束变化情况以及与星形细胞瘤之间的关系。

Preoperative evaluation of brain invasion by diffusion tensor tractography in gliomas

Objective To evaluate the brain invasion in gliomas by diffusion tensor tractography(DTT).Methods Diffusion tensor imaging was preoperatively performed in 35 patients who histologically confirmed gliomas.13 of the 35 tumors were low-grade gliomas and 22 were high-grade gliomas. Then the spatial relationship between the lesions and white matter fiber tracts around tumor was analyzed. displacement, continuity and injured conditions of white matter fiber were observed. Results White matter fiber tract in all lesions could be observed clearly. Three patterns of white matter fibers involvement were identified:displaced,infiltrated and destructed. White matter fiber tracts around low-grade gliomas were primarily displaced ,but were mainly infiltrated and destructed around high-grade gliomas. Conclusion DTT was useful for showing white matter fiber tracts,observing the shape changes stereographically,and evaluating the relationship with gliomas in vivo.