中西医结合治疗痰湿肥胖型多囊卵巢综合征患者的临床效果

目的:探讨中西医结合治疗对痰湿肥胖型多囊卵巢综合征(PCOS)患者内分泌紊乱及代谢的改善作用。方法:选取2017年1月至2018年6月芜湖市第二人民医院收治的辨证为痰湿型的PCOS患者60例作为研究对象,按照随机数字表法分为对照组和观察组,每组30例,比较2组患者经治疗后内分泌指标[卵泡刺激素(FSH)、促黄体生成素(LH)、LH/FSH],糖脂代谢指标[空腹血糖(FBG)、空腹胰岛素(FINS)、血清胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)]和临床疗效。结果:治疗后2组患者临床疗效比较,观察组治疗有效率为83. 33%,对照组治疗有效率为60. 00%,差异有统计学意义(P 0. 05)。治疗后2组患者内分泌指标FSH、LH、LH/FSH)、糖脂代谢指标FBG、FINS、TC、TG、LDL-C,体质量指数、腰臀比较治疗前降低,但HDL-C水平显著上升,差异有统计学意义(P 0. 05),治疗后观察组内分泌指标FSH、LH、LH/FSH)、糖脂代谢指标FBG、FINS、TC、TG、LDL-C,体质量指数、腰臀比较治疗前降低,但HDL-C高于对照组,差异有统计学意义(P 0. 05)。结论:中西医结合治疗对痰湿肥胖型PCOS患者的内分泌紊乱和代谢有显著改善作用。

Combined Treatment of Traditional Chinese and Western Medicine in Polycystic Ovary Syndrome of Phlegm Dampness and Obesity Syndrome

To investigate the improvement of endocrine disorders and metabolism in patients with phlegm dampness and obesity polycystic ovary syndrome(PCOS)treated by combined Chinese and western medicine.Methods:A total of 60 patients with PCOS of phlegm dampness and obesity syndrome admitted to Second People''s Hospital of Wuhu from January 2017 to June 2018 were divided into a control group and an observation group according to random number table,with 30 cases in each group.The endocrine,glycolipid metabolism and clinical efficacy were compared between the 2 groups after treatment.Results:Comparing the clinical efficacy between the 2 groups after treatment,the total effective rate was 83.33% in the observation group,and 60.00% in the control group,and the difference was statistically significant(P<0.05).After treatment,the endocrine index(FSH,LH,LH/FSH),glycolipid metabolism index(FBG,FINS,TC,TG,LDL-C),BMI and waist-to-hip ratio in the 2 groups were lower than before treatment,however,the HDL-C significantly increased with statistically significant difference(P<0.05).These indexes were significantly lower than those in the control group after treatment,and the HDL-C was higher than that in the control group(P<0.05).Conclusion:Combined treatment of Chinese and western medicine can significantly improve the endocrine disorders and metabolism in patients with PCOS of phlegm dampness and obesity syndrome.