| 蝉蜕对大鼠血液流变学影响的实验研究 |
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| 引用本文： | 刘善庭,李建美,王立赞,王清,梁玉记,朱凡河,李军,齐汝霞,于江,林丽文. 蝉蜕对大鼠血液流变学影响的实验研究[J]. 中医药学报, 2004, 32(3): 56-58 |
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| 作者姓名： | 刘善庭 李建美 王立赞 王清 梁玉记 朱凡河 李军 齐汝霞 于江 林丽文 |
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| 作者单位： | 济宁医学院,山东,济宁,272013 |
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| 摘 要： | 目的:观察中药蝉蜕对高脂血症大鼠血液流变学的影响.方法:Wistar大鼠随机分5组,其中高脂加蝉蜕水提液组采用高脂喂养,同时给予蝉蜕水提液灌胃,连续9天,末次给药后1小时取血检测血液流变各项指标并进行统计学处理.结果:高脂喂养的大鼠血清总胆固醇及甘油三酶水平明显升高,全血和血浆粘度、体外血栓形成、红细胞聚集指数显著增加;蝉蜕水提液对正常大鼠的血液流变学无显著影响,对高脂喂养的大鼠能显著降低其全血和血浆粘度、体外血栓形成、红细胞聚集指数、血清甘油三酯及总胆固醇水平.结论:蝉蜕具有显著改善高脂血症病理状态下的血液流变学作用.
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| 关 键 词： | 蝉蜕水提液 高脂血症 血液流变学 实验研究 |
| 文章编号： | 1002-2392(2004)03-0056-02 |
The effect of pedostracum cicadae on hernorheology in rats |
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| LIU Shan-ting,LI Jian-mei,WANG Li-zhan,et al.. The effect of pedostracum cicadae on hernorheology in rats[J]. Acta Chinese Medicine and Pharmacology, 2004, 32(3): 56-58 |
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| Authors: | LIU Shan-ting LI Jian-mei WANG Li-zhan et al. |
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| Affiliation: | LIU Shan-ting,LI Jian-mei,WANG Li-zhan,et al.Department of Pharmacology,Jirling Medical College,Jinling 272013,China |
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| Abstract: | The effect of periostracum cicadae on hemorheology in rats wasstudied.Water-extracted substance from PeriostracuIIl cicadaewas infused into the stomach of Wister rats feeded with hyperlipid for 9 days. Blood samples were taken andhemorheeological indexes were determined.The results demonstrated that periostracum cicadae markedly decreased blood viscosity,thrombosis in vitro, serum glycerinate and cholesterol contents,and red blood cell aggregation.As for the mechanism of periostracum cicadae on improving hemorheology,it remains to be in vestigated further. |
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| Keywords: | Periostracum cicadae Hemorheology Rat Hyperlipidemia |
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