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Vascular endothelial growth factor 936 C/T polymorphism in cancer patients. |
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| Authors: | A Eroglu S Gulec C Kurtman R Cam N Akar |
| Institution: | 1 Department of General Surgery and Surgical Oncology, Numune State Hospital, Konya 2 Biotechnology Institute of Ankara University, Tandogan, Turkey 3 Department of Radiation Oncology, Ankara University Medical School, Cebeci, Turkey 4 Department of General Surgery, Ankara University Medical School, Turkey 5 Department of Pediatric Molecular Genetic, Ankara University Medical School, Cebeci, Ankara, Turkey |
| Abstract: | Angiogenesis is an essential process in the development, growthand metastasis of malignant tumors 1]. Vascular endothelialgrowth factor (VEGF) plays an important role in the angiogenesis.Increased VEGF expression is associated with tumor growth andmetastasis, whereas inhibition of VEGF signaling results insuppression of both tumor-induced angiogenesis and tumor growth. The human VEGF |
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