| 奎硫平与氯氮平治疗精神分裂症对照研究 |
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| 引用本文： | 李定国,郑明勋,郑君杰,尚敏,刘似鸿,李和平,郑永毅.奎硫平与氯氮平治疗精神分裂症对照研究[J].临床精神医学杂志,2002,12(5):267-268. |
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| 作者姓名： | 李定国 郑明勋 郑君杰 尚敏 刘似鸿 李和平 郑永毅 |
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| 作者单位： | 1. 434415,湖北石首市久合垸医院精神科
2. 湖北石首市第一人民医院 |
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| 摘 要： | 目的 :评价奎硫平和氯氮平治疗精神分裂症的临床疗效与安全性。 方法 :对病程 <3年的 6 1例首次住院的精神分裂症患者 ,随机分为两组 ,分别选用奎硫平和氯氮平进行 8周治疗 ,采用阳性症状与阴性症状量表 (PANSS)评定疗效 ,用副反应量表 (TESS)评定副反应。 结果 :两药对精神分裂症疗效相当 ,副反应发生率及严重程度均相仿。 结论 :国产奎硫平对精神分裂症有肯定的疗效 ,且安全性较高
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| 关 键 词： | 奎硫平 氯氮平 精神分裂症 治疗 |
A comparative study between quetiapine and clozapine in the treatment of schizophrenia |
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| Li Dingguo,Zheng Mingxun,Zheng Junjie,et al..A comparative study between quetiapine and clozapine in the treatment of schizophrenia[J].Journal of Clinical Psychological Medicine,2002,12(5):267-268. |
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| Authors: | Li Dingguo Zheng Mingxun Zheng Junjie |
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| Institution: | Li Dingguo,Zheng Mingxun,Zheng Junjie,et al.Jiuheyuan Hospital of Shishou,Hubei 434415 |
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| Abstract: | Objective:To evaluate the effect and safety between quetiapine and clozapine in the treatment of schizophrenic patients. Method:Sixty-one schizophrenic patients who were first admitted in our hospital and with a course less than 3 years were randomly divided into two groups receiving quetiapine and clozapine respectively for 8 weeks.PANSS was used to evaluate the effect and TESS was used to evaluate the side effects. Results:Both groups had a similar effect.The occurent rate and severity of side effects were also similar in both groups. Conclusion:Quetiapine had a definite effect in the treatment of schizophrenia and had rather safety. |
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| Keywords: | Quetiapine Clozapine Schizophrenia |
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