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低分子肝素抗凝治疗急性胰腺炎
引用本文:焦华波,黄志强,姚咏明,乔治,王大东,谭向龙,王燕生.低分子肝素抗凝治疗急性胰腺炎[J].中华消化外科杂志,2008,7(2).
作者姓名:焦华波  黄志强  姚咏明  乔治  王大东  谭向龙  王燕生
作者单位:1. 解放军总医院第一附属医院普通外利,北京,100037
2. 解放军总医院全军肝胆外科研究所,北京,100853
摘    要:目的 了解低分子肝素抗凝治疗急性胰腺炎对预后的影响.方法 确诊急性胰腺炎并符合本研究标准的73例患者分为抗凝组(38例)及对照组(35例),观察其血清学检测指标和预后.结果 低分子肝素抗凝治疗能明显改善急性胰腺炎患者的血细胞及动脉血气指标,缩短住院时间,并能在一定程度上降低急性水肿型胰腺炎的重症化率、再手术率和病死率.不会加重重症急性胰腺炎的出血倾向.结论 低分子肝素抗凝治疗急性胰腺炎足安全、有效的,初步观察能明显改善患者的预后.

关 键 词:低分子肝素  抗凝治疗  急性胰腺炎

Anticoagulation treatment of acute pancreatitis with lower molecular weight heparin
JIA Hua-bo,HUANG Zhi-qiang,YAO Yong-ming,QIAO Zhi,WANG Da-dong,TAN Xiang-long,WANG Yan-sheng.Anticoagulation treatment of acute pancreatitis with lower molecular weight heparin[J].Chinese Journal of Digestive Surgery,2008,7(2).
Authors:JIA Hua-bo  HUANG Zhi-qiang  YAO Yong-ming  QIAO Zhi  WANG Da-dong  TAN Xiang-long  WANG Yan-sheng
Abstract:Objective To study the anticoagulation therapy of lower molecular weight heparin in the treatment of patients with acute pancreatitis.Methods Seventy-three patients with acute pancreatitis were divided into anticoagulation group(n=38)and control group(n=35).The serological indexes and prognosis of patients were detected.Results Anticoagulation treatment with lower molecular weight heparin significantly decreased the white blood cell count,increased the oxygen partial pressure in arterial blood,shoaened the duration of hospitalization,and reduced the aggravation rate,secondary operation rate and mortality of patients with acute pancreatitis.Conclusions Anticoagulation treatment with lower molecular weight heparin is safe,effective and can improve the prognosis of patients with acute pancreatitis.
Keywords:Lower molecular weight heparin  Anticoagulation treatment  Acute pancreatitis
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