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腔隙性脑梗塞与胰岛素抵抗关系的探讨
引用本文:王淼霞,胡治平,周文胜,邓景贵,宋涛. 腔隙性脑梗塞与胰岛素抵抗关系的探讨[J]. 心血管康复医学杂志, 2007, 16(1): 46-48
作者姓名:王淼霞  胡治平  周文胜  邓景贵  宋涛
作者单位:1. 湖南省马王堆医院,湖南,长沙市,410016
2. 中南大学湘雅第二医院神经内科
摘    要:目的:探讨腔隙性脑梗塞(CEI)患者是否存在胰岛素抵抗的问题。方法:测定35例CLI患者与35例健康对照者的血清空腹葡萄糖,空腹胰岛素,血脂(甘油三酯和低密度脂蛋白-胆固醇),并计算胰岛素敏感性指数。结果:CLI组胰岛素敏感性指数低于正常对照组(P〈0.01),而空腹血糖、胰岛素、血脂浓度高于对照组(P〈0.01~0.05)。结论:腔隙性脑梗塞患者存在胰岛素抵抗,胰岛素抵抗可能是腔隙性脑梗塞的危险因素之一。

关 键 词:脑梗塞  胰岛素  血糖
文章编号:1008-0074(2007)01-0046-03
收稿时间:2006-10-14
修稿时间:2006-10-14

Explore of correlation between cerebral lacunal infarction and insulin resistance
WANG Miao-xia,HU Zhi-ping,ZHOU Wen-sheng,DENG Jing-gui,SONG Tao. Explore of correlation between cerebral lacunal infarction and insulin resistance[J]. Chinese Journal of Cardiovascular Rehabilitation Medicine, 2007, 16(1): 46-48
Authors:WANG Miao-xia  HU Zhi-ping  ZHOU Wen-sheng  DENG Jing-gui  SONG Tao
Abstract:Objective:To explore whether there is insulin resistance in patients with cerebral lacunal infarction(CLI).Methods:The fasting blood glucose(FBG),insulin,blood lipid (total cholesterol and triglyceride) were examined in 35 patients and 35 healthy controls and their insulin sensitivity index(ISI) were calculated.Results:The ISI of the CLI group was significantly lower(P<0.01) than that in the control group while levels of FBG,insulin,blood lipid in CLI group increased(P<0.05~<0.01).Conclusion:There is insulin resistance in patients with cerebral lacunal infarction.Cerebral insulin resistance may be one of its risk factors for cerebral lacunal infarction.
Keywords:Cerebral infarction   Insulin   Blood glucose
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