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单肺移植治疗终末期肺气肿一例报告
引用本文:陈静瑜,郑明峰,何毅军,胡春晓,朱乾坤,陈若,朱艳红,陆明华.单肺移植治疗终末期肺气肿一例报告[J].中华器官移植杂志,2004,25(4):230-231.
作者姓名:陈静瑜  郑明峰  何毅军  胡春晓  朱乾坤  陈若  朱艳红  陆明华
作者单位:214073,江南大学附属医院无锡市第五人民医院肺移植组
摘    要:目的 探讨肺移植治疗终末期肺病肺气肿的手术适应证、手术方式、围术期的处理及术后生存率。方法 2002年9月28日为1例肺气肿、肺功能重度减损的患者进行左肺移植。结果 术后93h顺利脱机,术后第9d发生1次急性排斥,经大剂量甲泼尼龙冲击治疗后症状消退,术后40d胸部CT示左肺扩张良好,左肺血液灌注良好,术后肺功能明显改善,术后47d出院,现已恢复工作。结论 终末期肺气肿是肺移植最常见的手术适应证。单肺移植术后肺功能改善明显。

关 键 词:单肺移植  终末期  肺气肿  病例报告  适应证

Unilateral lung transplantation in end-stage emphysema:a case report
CHEN Jing-yu,ZHEN Ming-feng,HE Yi-jun,et al..Unilateral lung transplantation in end-stage emphysema:a case report[J].Chinese Journal of Organ Transplantation,2004,25(4):230-231.
Authors:CHEN Jing-yu  ZHEN Ming-feng  HE Yi-jun  
Institution:CHEN Jing-yu,ZHEN Ming-feng,HE Yi-jun,et al.Department of Thoracic Surgery,Jiangnan University,Wuxi No. 5 People's Hospital,Wuxi 214073,China
Abstract:Objective To explore the operation technique,patient selection,survival rate and perioperative management of lung transplantation for end-stage emphysema.Methods A 56-year-old male with end-stage emphysema was subjected to a left-lung transplantation in our hospital on 28 Sep.2002. The surgical technique used was similar to that mentioned in the literature.Results The patient weaned from ventilator on the next 93 h of operation. Immunosuppression included cyclosporine,mycophenolate mofetil.and corticosteroid. The acute rejection occurred on the 9 th day after operation and cured by bolus methylprednisolone given intravenously. His lung function was improved significantly and he was discharged from hospital 47 days after operation. After discharge from the hospital,the patients could return to an almost normal life.Conclusions End-stage emphysema is the most frequent indication for lung transplantation. The lung function was improved greatly after single-lung transplantations.
Keywords:Lung transplantation  Pulmonary emphysema
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