电针治疗抑郁症30例临床研究

目的:观察电针治疗抑郁症的临床疗效。方法:治疗组30例采用电针方法治疗,取穴百会、印堂,并配合辨证施穴,对照组用麦普替林。结果:两组治疗后汉密顿抑郁量表(HAMD)分值较治疗前均有显著下降(P<0.01),治疗后两组间比较差异无显著性(P>0.05)。两组总体疗效比较治疗组总有效率为96.7％,对照组为90.3％,组间比较差异无显著性(P>0.05)。两组治疗后中医症状积分较治疗前均有明显下降(P<0.01),且治疗后组间比较差异亦有显著性(P<0.05),治疗组明显优于对照组。Asberg抗抑郁药物副作用量表的分值下降情况治疗组亦明显优于对照组。两组治疗后血浆皮质醇(CORT)、内皮素(ET-1)含量均较本组治疗前明显下降(P<0.01),且基本恢复正常,治疗后两组间比较差异无显著性(P>0.05)。结论:电针疗法治疗抑郁症有与四环类抗抑郁药麦普替林相同的临床疗效,而且副作用小,对中医症状的改善优于麦普替林。

Clinical Study on Treatment of 30 Cases of Depression with Electroacupuncture

Purpose: To observe clinical therapeutic effects of electroacupuncture on depression. Methods: The treatment group was treated with electroacupuncture at Baihui, Yintang points based on differentiation of symptoms and signs, and the control group was treated with Maprotiline. Results: After treatment the score of the Hamilton Depression Scale decreased significantly as compared with that before treatment in the both groups OP<0. 01), with no significant difference between the two groups (P>0. 05). The total effective rate was 96. 7% in the treatment group and 90. 3% in the control group with no significant difference (P>0. 05). The cumulative scores of TCM symptoms after treatment in the two groups decreased significantly (P<0. 01), with significant difference between the two groups (P<0. 05), the treatment group being superior to the control group. According to the scoring of the Asberg scale for adverse effects of anti - depression medicines, the decrease of score in the treatment group was superior to that in the control group. Plasma cortisol and endothelin (ET - 1) contents after treatment in the two groups were decreased significantly as compared with before treatment (P < 0. 01), basically recovering normal, but with no significant difference between the two groups after treatment (P > 0. 05). Conclusion: Electroacupuncture has a similar therapeutic effect with Maprotiline on depression with less adverse effects, and the improvement of TCM symptoms is superior to that of Maprotiline.