浙江省部分地区2003年痢疾志贺菌菌群分布和耐药性分析

目的　了解浙江省志贺菌的菌型分布及耐药情况 ,提高防治措施的针对性 ,避免抗生素的滥用。方法　 15 8株志贺菌均按GB16 0 0 2 - 1995标准进行鉴定分型并采用kirby -Bauer法检测其对 14种抗生素的敏感性。结果　 15 8株志贺菌中福氏志贺菌 113株 (占 71 .5 2 % ) ;鲍氏志贺菌2 2株 (占 13. 92 % ) ;宋内志贺菌 14株 (占 8 .86 % ) ;痢疾志贺菌 9株 (占 5 . 70 % ) ;91株志贺菌对氨苄西林耐药最高达 95 .6 0 % ,其次为链霉素 (72. 5 3% ) ;对头孢他啶最敏感 ,其敏感性高达 95. 6 0 %。结论　近年来浙江省志贺菌的菌型分布及其对抗生素的敏感性均发生了明显的变化 ,医疗卫生部门应加强对志贺菌菌型及耐药性监测。

Analysis on Distribution of shigella Dysenteriae Flora and Drug Resistance in 2003 in Partial Regions of Zhejiang Province

Objective This analysis was to help understand the distribution of subtypes of Shigellae and their resistance to drugs so as to improve the pertinence of preventive and cure measures and avoid the abuse of antibiotics. Methods 158 strains of Shigellae was identified and grouped in terms of GB16002-1995 and Kirby-Bauer Methods was used to determine their sensitivities to 14 antibiotics.Results In 158 strains of Shigellae, there were 113 strains of Sh. Flexneri (71 52%), 22 strains of Sh. Boydii (13 92%), 14 strains of Sh. Sonnet (8 86%) and 9 strains of Sh. Dysenteriae (5 70%); 91 strains of shigellae were resistant to Amphicillin with the highest rate up to 95 60% and the next was Streptomycin (72 53%); bacteria were the most sensitive to Ceftazidime with a rate of 95 60%. Conclusion In recent years, there has been a notable change in the distribution of Shigella subtypes and their sensitivities to antibiotics in zhejiang province, and medical departments should strengthen the monitoring on subtypes of Shigellae and their drug resistance.