| 中药脱痂膏对烧伤创面的作用 |
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| 引用本文： | 葛绳德,刘世康,戴方平,韦多,王璐,白刚,陈玉林,孙家玲,俞为荣. 中药脱痂膏对烧伤创面的作用[J]. 第二军医大学学报, 1999, 20(3): 167-168 |
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| 作者姓名： | 葛绳德 刘世康 戴方平 韦多 王璐 白刚 陈玉林 孙家玲 俞为荣 |
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| 作者单位： | 第二军医大学长海医院烧伤科,上海,200433 |
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| 摘 要： | 目的：探讨外用中药脱痂膏对深度烧伤创面的脱痂机制。方法：取经脱痂膏和Ag-SD霜换药的深Ⅱ度烧伤创面组织标本及渗液，用抗CD68单抗标记深度烧伤创面组织中的巨噬细胞，并计数创面渗液细菌，比较两组间的差异。结果：使用脱痂膏的创面组织含有较多的CD68＋细胞(巨噬细胞)，而创面渗液细菌数量与Ag-SD组无明显区别。结论：脱痂膏通过招引巨噬细胞至创面局部，吞噬和分解坏死组织，从而达到脱痂的目的。
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| 关 键 词： | 烧伤 脱痂膏 巨噬细胞 |
The effect of Traditional Chinese Medicine Tuojiagao on burn wound |
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| Yu Weirong,Sun Jialing,Chen Yulin,Bai Gang,Wang Lu,Wei Duo,Dai Fangping,Liu Shikang,Ge Shengde. The effect of Traditional Chinese Medicine Tuojiagao on burn wound[J]. Former Academic Journal of Second Military Medical University, 1999, 20(3): 167-168 |
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| Authors: | Yu Weirong Sun Jialing Chen Yulin Bai Gang Wang Lu Wei Duo Dai Fangping Liu Shikang Ge Shengde |
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| Abstract: | Objective: To study the mechanism of Traditional Chinese Medicine Tuojiagao in cleaning necrotic and denatured tissue in deep burn wound. Methods: Two groups of patients with deep burn wound were studied: (1) Traditional Chinese Medicine Tuojiagao group, (2) Ag-SD frost group. Tissue and exudate of the wound were collected. Macrophages were marked with anti-CD68 antibody in tissue slides. The bacteria of wound exudate were counted. Results: The sections from wounds after using Tuojiagao have more CD68+ cells (macrophages) than Ag-SD group, and no difference of bacteria count was found between the 2 groups. Conclusion: Tuojiagao could clean necrotic tissue through recruiting macrophages to scavenge and break down it. |
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| Keywords: | burns Tuojiagao macrophages |
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