2002年我院药品不良反应报告分析

目的 :了解药品不良反应 (ADR )在我院的发生情况及其给患者造成的危害。方法 :对我院2002年298例ADR报告进行分类统计和分析。结果 :涉及ADR的药物共有165个品种 ,其中抗感染药物居首位 ,其次为抗肿瘤药物、心脑血管用药 ,中药制剂也较多。ADR病例中合并用药占28 5 % ,以静脉用药途径为主。主要的ADR类型为皮肤损害 ,其次是胃肠系统损害、发热等全身症状。重度ADR有20例 (占6 7 % )。结论 :应加强不易观察及慢性ADR的监测

Analysis of Adverse Drug Reactions Reported in Our Hospital

OBJECTIVE:To understand the situation of adverse drug reactions occured and the harm to paˉtients.METHODS:298cases reported in our hospital were classified,analysed and evaluated.RESULTS:165kinds of drug caused adverse drug reactions,of which anti-infective agents occupied the first place,anticancer agents the second,cardiovasˉcular and herbal agents induced ADRs very often too.The combined use of drugs accounted for28.5%in patients with ADRs.Most ADRs were induced by drugs given via intravenous route.The main types of ADRs were skin damage,gastro-intestinal damage,fever,etc.20cases had severe ADRs(6.7%).CONCLUSION:The adverse drug reactions difficult to observe and chronic ones should be paid more attention to.