| 碳离子射线诱导细胞凋亡的研究进展 |
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| 引用本文： | 刘成,程竞仪,章英剑.碳离子射线诱导细胞凋亡的研究进展[J].国际放射医学核医学杂志,2018,42(1):58-61, 79. |
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| 作者姓名： | 刘成 程竞仪 章英剑 |
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| 作者单位： | 1.200032 上海, 复旦大学附属肿瘤医院核医学科;2.201321, 上海市质子重离子医院核医学科 |
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| 基金项目： | 上海浦东新区科技发展基金PKJ2016-Y42 |
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| 摘 要： | 碳离子射线治疗肿瘤是利用其剂量分布优势，将能量集中于肿瘤组织释放，同时尽量避免损伤周围正常组织。相较于常规光子射线，碳离子不仅表现出上述物理学优势，还具有优越的生物学特性。笔者概述了碳离子射线在物理、生物学方面的特点，并着重综述了其在诱导细胞凋亡方面的进展。
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| 关 键 词： | 碳离子 细胞凋亡 肿瘤 |
| 收稿时间： | 2017-11-13 |
Progress in cell apoptosis induced by carbon ion beam |
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| Cheng Liu,Jingyi Cheng,Yingjian Zhang.Progress in cell apoptosis induced by carbon ion beam[J].International Journal of Radiation Medicine and Nuclear Medicine,2018,42(1):58-61, 79. |
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| Authors: | Cheng Liu Jingyi Cheng Yingjian Zhang |
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| Affiliation: | 1. Department of Nuclear Medicine, Fudan University Shanghai Cancer Center, Shanghai 200032, China;2. Department of Nuclear Medicine, Shanghai Proton and Heavy Ion Center, Shanghai 201321, China |
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| Abstract: | Compared with conventional radiation beams, heavy ion beam excels in its physical properties and biological characteristics. Limited energy release is absorbed by normal tissue before reaching the tumor while the energy bursts at the target region. This review presents the physical properties and biological characteristics of carbon ion beam and emphasizes recent progresses on apoptosis. |
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| Keywords: | Carbon ion Cell apoptosis Neoplasms |
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