2011-2016年云南省边境县手足口病流行特征聚类分析

目的 了解云南省边境县手足口病流行特征,为防控策略制定、跨境传染病联防联控工作提供参考依据。 方法 采用有序聚类和无序聚类方法,对2011-2016年云南省25个边境县的手足口病报告病例数和发病率,按不同月份、年龄段、县区进行分析。 结果 不同月份手足口病例数有序聚类可分为3类(1-3月、4-6月、7-12月各聚为一类)。无序分类可分为3类(1、4、7、9月; 5-6月及10-12月;2-3月及8月各聚为一类)。不同年龄段手足口病例数有序分类可分为3类(0~岁、1~3岁、4~岁以上各聚为一类)。无序分类可分为4类(1~岁、2~岁、0~岁及3~4岁、5~岁以上各聚为一类)。按手足口发病率可将25个县聚为4类:1类为瑞丽市、盈江县;2类为景洪市、勐海县、勐腊县、芒市;其余19个县可分别归为3类、4类。1类、2类县手足口病发病率高于3、4类。 结论 云南省25个边境县手足口病在不同时间、不同人群和不同地区之间流行具有差异性,应加强重点地区、重点人群的手足口病防控工作。

Cluster analysis on epidemiological characteristics of hand,foot and mouth disease in border counties of Yunnan Province, 2011-2016

Objective To investigate the epidemiological characteristics of hand, foot, and mouth disease (HFMD) in border counties of Yunnan Province so as to provide a basis for formulating prevention and control strategies and conducting cross-border collaborative surveillance of infectious disease. Methods Ordinal clustering method (OCM) and hierarchical clustering analysis method (HCAM) were employed to analyze the data of number and incidence of reported HFMD cases in 25 border counties of Yunnan Province during 2011-2016 regarding different months, age groups, counties and districts. Results The distribution of HFMD cases in different months was classified into three groups (the groups of January-March, April-June and July-December) based on OCM and three groups (the groups of January, April, July and September, May-June and October-December, February-March and August) based on HCAM. The distribution of HFMD cases in different age groups was classified into three groups (the age groups of 0- year, 1-3 years and 4- years and above) based on OCM and four groups (the age groups of 1- year, 2-years, 0- year and 3-4 years, and 5- years and above) based on HCAM. According to the average incidence rate of HFMD in 2011-2016, 25 border counties were divided into four levels (level I: Ruili City and Yingjiang County, level II: Jinghong City, Menghai County, Mengla County and Mang City and levels III and IV: the rest of the counties). The incidence rates of HFMD in counties of levels I and II were significantly higher than those in counties of levels III and IV. Conclusions Among the 25 border counties in Yunnan Province, the epidemiological characteristics of HFMD cases in different months, age groups and counties are diverse. It is necessary to strengthen HFMD prevention and control among the key counties and target population.