基于限定日剂量和帕累托图法分析某院2016年重点监控药品的使用情况

目的:了解重点监控药品管控成效,为进一步控制重点监控药品使用量提供参考。方法:参照2016年《四川省卫生和计划生育委员会关于建立医疗机构重点监控药品管理制度的通知》1]所规定的重点监控药品制定某院重点监控药品目录,在对监控前后重点监控药品的销售金额进行回顾性分析的基础上,引入限定日剂量(DDD)的概念,采用DDD方法分析监控前后重点监控药品使用情况,并通过帕累托图分析法对实施重点监控后所监控药品进行分析,提示其中的主要影响品种。结果:经过对重点监控药品的专项整治,该院重点监控药品销量及DDDs下降有显著性,说明该院对重点监控药品的专项整治有效。实施监控后,重点监控药品销售金额的帕累托图分析显示在36个品规中14个品规构成主要因素。该院重点监控药品经整治后,主要影响重点监控药品销售金额的药品为兰索拉唑注射剂(17.84%),泮托拉唑注射制剂(16.49%),脑苷肌肽注射液(5.84%)。结论:临床药师对整治前后重点监控药品进行回顾性分析,重点监控药品使用情况改善有显著性,但具体分析后仍有不合理使用现象存在,应进一步优化管理。

Analysis of key inspection drugs in a tertiary A grade hospital in 2016 based on DDD and Pareto chart

OBJECTIVE To give reference materials for further control of those drugs by analyzing the management effect of key inspection drugs. METHODS The list of key inspection drugs drawn up by Health and Family Planning Commission of Sichuan Province was referred to draw up the key inspection drug list in Chengdu Second People's Hospital, and add up the sales volumes before and after the control. DDD analysis was performed for drugs used in 2016. Pareto chart analysis was performed for key inspection drugs used in late 2016. RESULTS The control of key inspection drugs in this hospital was effective as there were statistical differences between the sales volumes before and after the control. The differences between the DDDs before and after the control also had statistical significance. After the control, of all 36 drugs, 14 drugs were major drugs. In late 2016, 3 top key inspection drugs were Lansoprazole for Injection (17.84%), Pantoprazole Sodium for Injection (16.49%) and Cattle Encephalon Glycoside and Ignotin Injection (5.84%). CONCLUSION It has statistical significance for clinical pharmacists to analyze the use of key inspection drugs before and after the control to improve the use of drugs and conduct the control of key inspection drugs. However, there are also some unreasonable uses of those drugs, and more useful management measures are needed.