| 分化型甲状腺癌131I显像假阳性的原因分析 |
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| 引用本文： | 南楠,朱小华. 分化型甲状腺癌131I显像假阳性的原因分析[J]. 国际放射医学核医学杂志, 2018, 42(1): 62-68. DOI: 10.3760/cma.j.issn.1673-4114.2018.01.012 |
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| 作者姓名： | 南楠 朱小华 |
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| 作者单位： | 430030 武汉, 华中科技大学同济医学院附属同济医院核医学科 |
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| 摘 要： | 分化型甲状腺癌患者131I全身显像及SPECT显像对于判定病情、决定下一步治疗方案具有重要意义。然而，显像有时会出现假阳性结果，即异常浓聚灶并不是残留的甲状腺组织或甲状腺癌转移灶。系统全面地了解这些假阳性分布及原因有助于图像的准确判读，更可避免患者后续不必要或过大剂量的131I治疗。笔者就分化型甲状腺癌131I全身显像假阳性情况分布、特点及其可能的机制展开综述。
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| 关 键 词： | 分化型甲状腺癌 碘放射性同位素 全身显像 体层摄影术 发射型计算机 单光子 假阳性 |
| 收稿时间： | 2017-11-03 |
Analysis of the false positive findings on 131I whole-body scan in differentiated thyroid cancer |
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| Nan Nan,Xiaohua Zhu. Analysis of the false positive findings on 131I whole-body scan in differentiated thyroid cancer[J]. International Journal of Radiation Medicine and Nuclear Medicine, 2018, 42(1): 62-68. DOI: 10.3760/cma.j.issn.1673-4114.2018.01.012 |
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| Authors: | Nan Nan Xiaohua Zhu |
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| Affiliation: | Department of Nuclear Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China |
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| Abstract: | 131I whole-body scan and SPECT imaging in patients with differentiated thyroid cancer can provide information regarding metastasis and prognosis, and assist in treatment planning. However, false positive uptake, which is not residual thyroid tissue or metastases, is sometimes encountered. Unless recognized as a false positive, 131I uptake may result in diagnostic error and lead to administration of an unnecessary therapeutic dose. This review discussed various possibilities of false positive uptake on 131I whole-body scan, as well as the underlying causes and mechanisms. |
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