2015-2016年上海市宝山区手足口病流行特征的聚类分析

目的 分析2015-2016年上海市宝山区手足口病流行特征,探讨疫情变化规律,为制定防控策略提供科学依据。 方法 采用系统聚类方法对宝山区2015-2016年手足口病疫情和病原学资料进行分析。 结果 2015-2016年上海市宝山区共报告手足口病9 475例,年均发病率为236.41/10万。不同月份发病数、不同年龄组发病数、不同地区发病率和不同月份聚集性疫情报告数均可聚成3类。5-7月为发病高峰(占44.16%),人群主要集中在1~4岁年龄组(占73.73%),发病率最高的地区为顾村镇、杨行镇和罗店镇;聚集性疫情在5-6月报告最多,2015-2016年期间本区手足口病优势病原为柯萨奇病毒A组6型(coxasckievirus A6,CoxA6)。 结论 2015-2016年上海市宝山区手足口病发病仍处于高强度流行状态,流行特征具有时间、地区、人群差异,优势病原为CoxA6,应采取具有针对性的防控策略和措施。

Clustering analysis on epidemiological characteristics of hand,foot andmouth disease in Baoshan District,Shanghai, 2015-2016

Objective To analyze the epidemiological characteristics of hand, foot, and mouth disease (HFMD) in Baoshan District of Shanghai from 2015 to 2016, to explore its epidemic changing patterns, and to provide a scientific basis for formulating prevention and control strategies. Methods Hierarchy clustering method was employed to analyze the data regarding HFMD incidence and etiology in Baoshan District during 2015-2016. Results A total of 9,475 HFMD cases were reported in Baoshan District from 2015 to 2016, with the average incidence rate being 236.41/100,000. Number of cases in different months, number of cases in different age groups, incidence rates in different streets/towns and reported number of clusters of epidemic were gathered into 3 categories. HFMD had an epidemic peak during May and July (44.16%).The incidence rate was found to be the highest in the age groups of 1-4 years (73.73%).Towns as Gucun, Yanghang and Luodian had the highest incidence rate. The maximum reported cluseters of epidemic appeared in May-June, andcoxasckievirus A6(CoxA6) was the dominant pathogen of HFMD in 2015-2016. Conclusions HFMD was highly endemic in Baoshan District of Shanghai City from 2015 to 2016, and its epidemiological characteristics showed differences in time, region and population. The dominant pathogen was CoxA6. It is necessary to take targeted prevention and control strategies and countermeasures.