| 慢性丙型肝炎患者血清自身抗体检测及其临床意义研究现状* |
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| 引用本文： | 姜宏达 综述,周海舟 审校.慢性丙型肝炎患者血清自身抗体检测及其临床意义研究现状*[J].实用肝脏病杂志,2018,21(5):817-820. |
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| 作者姓名： | 姜宏达 综述 周海舟 审校 |
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| 作者单位： | 150081 哈尔滨市 哈尔滨医科大学（姜宏达）; 附属第一医院检验科（周海舟） |
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| 基金项目： | 黑龙江省科学技术研究发展计划项目（编号：2016D02-11） |
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| 摘 要： | 经常发现慢性丙型肝炎病毒（HCV）携带者血清非器官特异性自身抗体（non-organ-specific autoantibodies,NOSA）和抗甲状腺自身抗体（anti-thyroid autoantibodies ATAB）阳性,伴有以自身免疫耐受性丧失为特征的一组自身免疫性疾病,本文将重点介绍这方面的研究进展。
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| 关 键 词： | 丙型肝炎 自身免疫 抗体抗核 自身免疫性甲状腺疾病 干扰素-α |
| 收稿时间： | 2018-01-22 |
Serum autoantibodies in patients with hepatitis C |
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| Jiang Hongda,Zhou Haizhou..Serum autoantibodies in patients with hepatitis C[J].Journal of Clinical Hepatology,2018,21(5):817-820. |
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| Authors: | Jiang Hongda Zhou Haizhou |
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| Institution: | Harbin Medical University,Harbin 150081, Heilongjiang Province,China |
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| Abstract: | Serum non-organ-specific autoantibodies（NOSA） and anti-thyroid autoantibodies（ATAB） were often found positive in patients with chronic hepatitis C and hepatitis C viral carriers. The patients were characterized by loss of autoimmune tolerance, which might cause a set of autoimmune diseases in this setting. The progress in this field will be discussed in this article. |
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| Keywords: | Hepatitis C Autoimmunity Antinuclear antibodie Autoimmune thyroid diseases Interferon-alpha |
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