渗透树脂和氟化物对早期牙釉质龋治疗效果的比较

摘要： 目的 比较渗透树脂和氟化物治疗对早期人工牙釉质龋治疗的效果。方法 60 颗完好的牛切牙样本制成牙釉质标本并浸入到脱矿液中 24 h 制成牛切牙釉质龋。随机数字表法分为 4 组 （n=15）： CON （对照） 组， 浸润在人工唾液； DF 组， 每天 0.05% 氟化钠处理； WF 组， 每周涂布 2% 氟化物凝胶； IC 组， 渗透树脂处理。处理结束后， 分别测量各组样本 4 周、 8 周及再次脱矿后表面的显微硬度及 4 周后的渗透深度。结果 显微硬度评估显示， 各组基线值 （白斑病变形成后） 差异无统计学意义 （P＞0.05）， 经过治疗后， IC 组第 4 周， DF 组、 WF 组第 8 周显微硬度值达到最高峰， IC 组在各个时间段均明显高于其他组 （P＜0.05）。4 周后各组渗透深度的百分比显示， DF、 WF、 IC 组均明显高于对照组 （P＜0.01）， IC 组的渗透深度百分比均明显高于 DF 组和 WF 组 （P＜0.05）， DF 组和 WF 组间差异无统计学意义 （P＞0.05）。结论 对早期牙釉质龋渗透树脂， 渗透百分比明显高于氟化物治疗。

Comparison of the therapeutic effects between penetrating resin and fluoride on early enamel caries

Abstract：Objective To investigate the therapeutic effects of penetrating resin and fluoride on early enamel caries. Methods Sixty intact bovine incisors were immersed in demineralized solution for 24 hours to make bovine incisor enamel caries. The specimens were divided into four groups (n=15 for each group) according to the treatment methods: control group (CON) - immersion in artificial saliva, DF group-immersion in 0.05% fluoride solution daily, WF group-2% fluoride gel weekly and IC group-resin infiltration. After processing for four and eighe weeks, the microhardness of the surface of each group was measured. After the treatment for four weeks, the depth of penetration and the microhardness of the samples were measured. After 8-week treatment, all samples were reintroduced into the demineralized solution for 24 hours and the microhardness of the samples was measured again. Results Results of microhardness assessment showed that there were no significant differences in baseline values (after white spots) between four groups (P＞0.05). After treatment for four weeks the microhardness value reached the peak in IC group. After treatment for eight weeks the microhardness values reached the peak in DF group and WF group. The values of microhardness were significantly higher at different time points in IC group than those of other groups (P＜0.05). After 4-week treatment, the percentages of penetration depth were significantly higher in DF, WF and IC groups than those of control group (P＜0.01). The penetration depth was significantly higher in IC group than that of DF group and WF group (P＜0.05). There was no significant difference in the penetration depth between DF group and WF group (P＞0.05). Conclusion For the early enamel caries penetration resin, the penetration percentage is significantly higher than the fluoride treatment.