不同型号IOL Master对硅油眼的生物测量比较

目的 比较IOL master 500及IOL master 700测量硅油眼患者眼轴长度、角膜曲率、前房深度等参数的差异。设计 前瞻性病例系列。研究对象 选取2017年9月于北京同仁医院眼科住院的硅油填充术后患者34例（38眼）。方法 对患眼先后应用IOL master 500及IOL master 700测量眼轴长度（AL）、角膜曲率（K）及前房深度（ACD），应用SPSS22.0对两组测量结果进行配对t检验及一致性检验，并应用MedCalc软件对两组数据进行Bland-Altman分析。主要指标 AL、平均角膜曲率（Km）及ACD。结果 34例（38眼）硅油眼，眼轴检出率IOL master 500为89.5%（34/38），IOL master 700为97.4%（37/38）；两仪器检出的AL、Km、ACD均无显著差异，AL分别为（25.05±3.37）mm、（25.03±3.35）mm（t=1.351，P=0.186），Km分别为（43.42±3.10）D、（43.45±2.99）D（t=-0.393，P=0.697），ACD分别为（3.42±0.80）mm、（3.56±1.01）mm（t=-1.184，P=0.247）。一致性检验，AL（ICC＝1.000），Km（ICC＝0.996），ACD（ICC＝0.857）。Bland-Altman分析95%一致性界限AL（-0.1514 mm，0.1920 mm），Km（-0.7723 D，0.7205 D），ACD（-1.4057 mm，1.1222 mm），分别有2.94%（1/34）、8.82%（3/34）及3.45%（1/29）的点在95%一致性界限以外。结论 IOL master 500及IOL master 700两种光学生物测量仪对硅油眼进行生物测量，眼轴长度及平均角膜曲率测量结果一致性较高，IOL master 700具有比IOL master 500更高的硅油眼眼轴检出率。（眼科， 2018, 27： 349-352）

Comparison of IOL Master 500 and IOL Master 700 for measuring parameters in silicone oil filled eyes

Objective To compare two optical biometric instruments IOL master 500 and IOL master 700 for measuring the axial length(AL), keratometry(K) and anterior chamber depth(ACD) in silicone oil filled eyes. Design Prospective case series. Participants 34 cases (38 eyes) of silicone oil filled eyes were selected in September 2017 in Beijing Tongren Hospital Ophthalmology Inpatient Department. Methods The AL, K and ACD were measured using IOL master 500 and IOL master 700 successively. The results of two groups were compared using paired t test, reliability analysis, and MedCalc software was used to do the Bland-Altman analysis. Main Outcome Measures AL, mean keratometry(Km) and ACD. Results The AL detection rate of IOL master 500 and IOL master 700 were 89.5% (34/38) and 97.4% (37/38), respectively. There was no significant differences in AL, Km and ACD between IOL master 500 and IOL master 700. The AL was (25.05±3.37)mm and (25.03±3.35)mm (t=1.351, P=0.186) respectively. The Km was (43.42±3.10)D and (43.45±2.99)D (t=-0.393, P=0.697), and the ACD was (3.42±0.80)mm and (3.56±1.01)mm (t=-1.184, P=0.247), respectively. Reliability analysis of the two groups demonstrated AL(ICC＝1.000), Km(ICC＝0.996) and ACD(ICC＝0.857). The 95% consistency limits of Bland-Altman analysis showed AL(-0.1514 mm, 0.1920 mm), Km(-0.7723D, 0.7205D), ACD(-1.4057 mm, 1.1222 mm) and there were 2.94% (1/34), 8.82%(3/34) and 3.45%(1/29) of the points outside 95% consistency limit respectively. Conclusion There were no statistically significant differences in the axial length and mean keratometry of silicone oil filled eyes measured with IOL master 500 and IOL master 700. IOL master 700 had a higher detection rate of axial length in silicone oil filled eyes than IOL master 500 did. （Ophthalmol CHN，2018, 27： 349-352）