CT引导经皮微波消融联合肝动脉栓塞治疗肝癌的临床疗效

目的:观察CT引导下微波消融联合肝动脉栓塞对肝癌的治疗效果。方法:以2011年3月至2015年6月在我院接受治疗的肝癌患者为观察对象。根据其治疗方式分为肝动脉栓塞组（40例）和联合治疗组（45例），其中肝动脉栓塞组给予单纯肝动脉栓塞，联合治疗组给予肝动脉栓塞联合CT引导下肝癌微波消融。观察两组患者的治疗效果，比较两组患者治疗前后肝功能水平和生存率的差异。结果:联合治疗组治疗有效率明显高于肝动脉栓塞组，差异具有统计学意义（P＜0.05）；两组患者治疗前的谷丙转氨酶（ALT）、谷草转氨酶（AST）和结合胆红素（DBIL）等指标水平无明显差异，治疗后，两组患者的上述指标均较治疗前降低，且联合治疗组降低更明显（P＜0.05）；联合治疗组1年、2年和3年生存率均高于肝动脉栓塞组，差异具有统计学意义（P＜0.05）。结论:CT引导下微波消融联合肝动脉栓塞对肝癌有较好的治疗效果，可明显改善患者肝功能，提高其远期生存率。

Clinical efficacy of ultrasound-guided percutaneous microwave ablation combined with transcatheter arterial chemoembolization for hepatocellular carcinoma

Objective:To observe the therapeutic effect of ultrasound-guided percutaneous microwave ablation combined with hepatic artery embolization in the treatment of liver cancer.Methods:Liver cancer patients treated in our hospital from March 2011 to June 2015 were selected as object.According to the treatment methods，which were divided into hepatic artery embolization group(40 cases) and treatment group(45 cases)，hepatic artery embolization group was given simple hepatic artery embolization，combined therapy group was treated with ultrasound-guided percutaneous microwave ablation combined with transcatheter arterial chemoembolization.To observe the therapeutic effect of two groups of patients，compared with two groups of patients before and after treatment of liver function and survival rate.Results:The effective rate of combined treatment group was significantly higher than that of the hepatic arterial embolization group，and the difference was statistically significant(P＜0.05).Patients in the treatment group before the alanine aminotransferase(ALT)，aspartate aminotransferase(AST)，combined bilirubin(DBIL) and index level had no significant difference.After treatment，the above indexes of the two groups of patients were compared with those before treatment reduced and combined treatment group reduced more significantly(P<0.05).The 1 year，2 years and 3 years survival rates of the combined treatment group were higher than those of the hepatic arterial embolization group，and the difference was statistically significant(P＜0.05).Conclusion:Ultrasound-guided percutaneous microwave ablation combined with hepatic artery embolization for the treatment of liver cancer，can significantly improve the liver function，improve the long-term survival rate.