全程优化护理在降低MAC30阳性乳腺癌化疗患者消化道反应中的应用

目的:探讨全程优化护理在降低MAC30阳性乳腺癌化疗患者消化道反应中的应用价值。方法:2012年9月到2016年1月选择在我院行诊治的MAC30阳性乳腺癌患者78例作为研究对象，根据随机信封抽签原则分为观察组与对照组各39例，对照组给予常规治疗与护理，观察组在对照组干预基础上给予积极地全程优质护理，观察周期为3个月。结果:观察组与对照组化疗期间的用药依从性分别为100.0%和87.2%，观察组的用药依从性明显高于对照组(P<0.05)。观察组化疗期间的恶心呕吐、便秘、腹泻等发生率分别为23.1%、20.5%和5.1%，对照组分别为89.7%、61.5%和33.3%，观察组明显低于对照组(P<0.05)。观察组与对照组化疗后的生活质量评分分别为（57.55±10.25）分和（70.14±9.89）分，都明显低于化疗前的（87.49±11.48）分和（87.10±10.41）分(P<0.05)，在化疗后，对比两组生活质量评分，能够看出观察组明显低于对照组(P<0.05)。结论:全程优化护理在降低MAC30阳性乳腺癌化疗患者中的应用能降低发生消化道反应的概率，提升患者的用药依从性，进而改善其生活质量。

Application of whole course optimization nursing in reducing digestive tract reaction of patients with MAC30 positive breast cancer with chemotherapy

Objective:To investigate the application values of whole course optimization nursing in reducing digestive tract reaction of patients with MAC30 positive breast cancer with chemotherapy.Methods:From September 2012 to January 2016，78 cases of MAC30 positive breast cancer in our hospital for diagnosis and treatment were selected as the research objects.All the cases were divided into observation group and control group with 39 cases in each group according to the random draw envelope principle.The control group was given routine treatment and nursing，and the observation group was given the whole course optimization nursing based on the control group for 3 months.Results:The compliance rate in the observation group and the control group during chemotherapy were 100.0% and 87.2%，respectively，and the compliance of the observation group was higher than that of the control group (P<0.05).The incidence of nausea，vomiting，constipation and diarrhea in the observation group during chemotherapy were 23.1%，20.5% and 5.1%，respectively,and 89.7%，61.5% and 33.3% in control group，so these of the observation group were significantly lower than that of the control group (P<0.05).The scores of quality of life in the observation group and the control group after chemotherapy were (57.55±10.25) scores and (70.14±9.89) scores,which were significantly lower than those before treatment of (87.49±11.48) scores and (87.10±10.41) scores (P<0.05).The quality of life score in the observation group after chemotherapy was significantly lower than the control group (P<0.05).Conclusion:The application of whole course optimization nursing in MAC30 positive breast cancer patients can reduce the occurrence of digestive tract reaction and improve the compliance of medication during chemotherapy，so as to improve the quality of life of patients.