病原菌影响巨噬细胞极化的研究进展

巨噬细胞作为固有免疫系统中的重要一员，具有吞噬、抗原呈递、杀伤病原体等功能，在早期控制病原菌感染中发挥重要作用。病原菌可诱导巨噬细胞发生M1/M2型极化而参与机体对病原菌感染的免疫应答。病原菌运用不同的策略诱导巨噬细胞极化，对感染性疾病转归产生重要的影响。

Advances in the study of pathogens affect macrophage polarization

Macrophages,an important member of the innate immune system,have the functions of phagocytosis,antigen presentation and pathogen killing and play an important role in the early control of pathogen infection.Pathogen can induce M1/M2 macrophages polarization and participate in the body′s immune response to pathogen infection.Pathogens use different strategies to induce macrophage polarization and have an important impact on the outcome of infectious diseases.