犬上颌窦内提升植骨与不植骨的成骨效果比较

目的:比较内镜下犬上颌窦内提升植骨与不植骨的成骨效果。方法:随机将6只比格犬（共12侧上颌窦）分为2组, A组为上颌窦内提升+即刻种植（3.5 mm×8 mm）,B组为上颌窦内提升+Bio-Oss（0.8 mL）+即刻种植（3.5 mm×8 mm）。利用CT、Micro-CT以及组织学评价2组术后上颌窦内和种植体周围成骨情况。采用SAS 9.0软件包对数据进行统计学分析。结果:术后切口愈合良好,无感染等并发症发生。A组术后即刻、3个月的CT数据重建上颌窦内成骨体积和密度显著低于B组。Micro-CT和组织学切片均证实,A组的成骨仅在种植体周围的下部,而中部和上部未见明显骨质;而B组的种植体周围均包绕着适量骨质。2组中上部和中部新骨面积存在显著差异（P<0.05）;下部新骨面积无显著差异（P>0.05）。结论:上颌窦内提升不植骨时仅在窦底有一定量的新骨形成,为了达到良好的术后和远期效果,建议在行内提升术时适当植入骨粉。

Osteogenesis effect of maxillary sinus floor lift in Beagle dogs

PURPOSE:To evaluate the osteogenesis effect of maxillary sinus floor lift in Beagle dogs with bone grafting and without bone grafting. METHODS: Twelve operations (bilateral and randomly chosen) were done in 6 Beagle dogs in group A and group B (implanted Bio-Oss 0.8 mL), in which the operation was performed using maxillary sinus floor lift and immediate implant(3.5 mm×8 mm) placement. Postoperative CT scans, Micro-CT and histological analysis for all animals were conducted to evaluate the osteogenesis in the maxillary sinus floor and around the implants. SAS 9.0 software package was used for statistical analysis. RESULTS: The animals' incision healed well and without any complication such as infection. The osteogenic volume and bone density in group A was significantly lower than in group B on postoperative CT and 3 months after surgery's data. Micro-CT and histological analysis demonstrated that the osteogenesis in group A only surrounded the lower part of the implants, but surrounded all of the implants in group B. There was significant difference in new bone volume of the top and middle part of the implants between group A and B, but there was no significant difference in the lower part of the implants. CONCLUSIONS: There is certain amount of new bone formation at the lower part of the implants after maxillary sinus floor lift without bone implanting. To achieve better postoperative and long-term results, it is recommended to implant appropriate bone materials during maxillary sinus floor lift.