基于QLQ-C30与QLQ-PR25量表的前列腺癌患者生命质量影响因素

目的 探讨前列腺癌患者生命质量的影响因素.方法 共收集115例前列腺癌患者, 采用欧洲癌症研究与治疗组织 (EORCT) 开发的生命质量核心量表 (QLQ-C30 V3.0) 中文版和前列腺癌生命质量特异模块量表QLQ-PR25评估患者生命质量, 采用单因素和多重线性回归分析生命质量的影响因素.结果 不同年龄、文化程度、家庭经济状况的前列腺癌患者在部分领域生命质量得分的差异有统计学意义 (P<0.05) , 且患者年龄、文化程度、家庭经济状况与其生命质量得分相关 (P<0.05) , 但复相关系数均较小.结论 影响前列腺癌患者生命质量的因素有年龄、文化程度、家庭经济状况, 但这3个指标不能很好解释患者的生命质量, 应该还存在其他影响因素.

Influence Factors of Life Quality of Prostate Cancer Patients Based on QLQ-C30 and QLQ-PR25

Objective To investigate the factors influencing the life quality of prostate cancer patients based on QLQ-C30 and QLQ-PR25. Me thod A total of 115 prostate cancer patients was recruited. QLQ C30 V3.0 (Chinese version) , a scale of core life quality developed by European organization for research and treatment of cancer (EORCT) , and QLQ-PR25, a scale of prostate specific module, were used to assess the life quality of the patients and single factor and multiple linear regression were applied to analyse the influence factors.Re s ults There were significant differences in some life quality scores of the patients with different age, education level, family financial status (P <0.05) , and they were correlated (P <0.05) but with low multiple correlation coefficients. Conclus ion Age, education level, family financial status are the influence factors to the life quality of prostate cancer patients, but the contributions seem to be limited and further studies on other factors are needed.