高粘度骨水泥在肿瘤颈椎骨转移中的应用

目的:探讨高粘度骨水泥在肿瘤颈椎骨转移中的应用效果。方法:回顾性分析我院2013年1月至2017年1月行高粘度骨水泥治疗的30例肿瘤颈椎骨转移患者相关资料，评价临床疗效、并发症情况，并测定治疗前后不同时间点测量数值评分量表（NRS）及Karnofsky评分。结果:骨水泥注射成功率100.00%，骨水泥平均用量4.0 ml；发生无症状骨水泥外漏1例；术后影像学检查显示骨水泥完全填充椎体28例，大部分椎体填充2例；与术前24 h比较，术后24 h、1周、3个月NRS评分均显著低，Karnofsky评分显著高，差异有统计学意义（P<0.05）；术后6个月Karnofsky评分（52.68±16.39）分，较术前24 h的（55.67±8.92）分差异无统计学意义（P>0.05）。结论:骨水泥注射能迅速减轻肿瘤颈椎骨转移引发的疼痛，能有效提高患者近期存活质量。

The application of high-viscosity bone cement in treatment of cervical vertebral metastasis

Objective:To investigate the application effect of high-viscosity bone cement in treatment of cervical vertebral metastasis.Methods:The related data of 30 patients with cervical vertebral metastasis treated in our hospital from January 2013 to January 2017 with high-viscosity bone cement were analyzed retrospectively.The clinical efficacy and complications were evaluated.The numerical rating scale (NRS) scores and Karnofsky scores were determined at different time points before and after treatment.Results:The success rate of bone cement injection was 100.00%，and the average dosage of bone cement was 4.0 ml.There was 1 case of asymptomatic bone cement leakage，and postoperative imaging examination showed that bone cement completely filled the vertebral bodies in 28 cases and filled most vertebral bodies in 2 cases.NRS scores at 24 h，1 week and 3 months after operation were significantly lower and Karnofsky scores were significantly higher than those at 24 h before operation (P<0.05).There was no significant difference in Karnofsky score at 6 months after operation (52.68±16.39)，compared with that at 24 h before operation (55.67±8.92) (P>0.05).Conclusion:Bone cement injection can relieve the pain caused by cervical vertebral metastasis，which can improve the short-term quality of life of patients.